GNH USA

Europe — EMA

Paracetamolo Kabi

GNH USA supplies Paracetamolo Kabi (Paracetamol), a analgesic/antipyretic for pain and fever. Request a quote for global supply to hospitals worldwide.

Paracetamol

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What is Paracetamol?

Paracetamol, the active ingredient in Paracetamolo Kabi, is an analgesic presented as an intravenous solution for intravenous use. It treats pain and fever in adult and pediatric patients as directed by a healthcare professional.

GNH USA supplies Paracetamolo Kabi as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Paracetamol used for?

Paracetamol is used as an analgesic and antipyretic to manage pain and fever.

- Pain: provides relief of moderate to severe acute pain. - Fever: reduces elevated body temperature. - Post‑operative pain: offers analgesia after surgical procedures. - Headache: alleviates tension‑type and mild migraine headaches. - Musculoskeletal pain: eases discomfort from strains, sprains and arthritis.

What are the side effects of Paracetamol?

Paracetamol administered intravenously may be associated with several adverse reactions.

Common Side Effects: - Injection site pain: mild discomfort at the infusion site. - Nausea: transient feeling of queasiness. - Mild hypotension: slight drop in blood pressure during infusion. - Headache: occasional mild headache.

Serious or Rare Side Effects: - Anaphylaxis: severe allergic reaction requiring immediate medical attention. - Severe hepatic injury: potential liver damage, especially with overdose. - Stevens‑Johnson syndrome: rare but serious skin and mucous membrane disorder.

What precautions apply to Paracetamol?

Paracetamolo Kabi should be used with attention to patient‑specific factors and proper handling.

- Hepatic impairment: adjust dose or avoid use in severe liver disease. - Renal function: monitor kidney parameters in patients with existing renal insufficiency. - Hypersensitivity: do not administer to individuals with known allergy to paracetamol or formulation excipients. - Cardiovascular stability: use cautiously in patients prone to hypotension. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake the solution.

What does Paracetamol interact with?

Paracetamolo Kabi can interact with other medicines, requiring vigilance.

Major Interactions (Avoid): - Concurrent hepatotoxic drugs: increase risk of liver injury. - High‑dose aspirin or NSAIDs: elevate potential for renal toxicity. - Anticoagulants (e.g., warfarin): may enhance bleeding tendency.

Moderate Interactions (Monitor Closely): - Alcohol consumption: can potentiate hepatic effects. - Other antipyretics (e.g., ibuprofen): monitor total dose to avoid overdose. - Diuretics: watch for additive hypotensive effects.

Frequently asked questions

What is Paracetamolo Kabi used for?+
Paracetamolo Kabi is an intravenous formulation of paracetamol used to provide rapid relief of pain and to reduce fever in hospital settings. It is administered under medical supervision for conditions such as postoperative pain, acute febrile episodes, and other situations where oral therapy is unsuitable.
How does paracetamol work in this product?+
Paracetamol works by inhibiting cyclooxygenase enzymes in the central nervous system, which lowers the production of prostaglandins responsible for pain signaling and fever generation. This central action reduces the hypothalamic temperature set‑point and diminishes nociceptive transmission, resulting in analgesic and antipyretic effects.
What is the usual dose of Paracetamolo Kabi?+
The appropriate dose of Paracetamolo Kabi is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and renal or hepatic function. Healthcare professionals calculate the exact infusion rate and total amount required for each individual case.
Is Paracetamolo Kabi safe during pregnancy or breastfeeding?+
Safety data for intravenous paracetamol in pregnancy and lactation are limited, and the product’s pregnancy category is not established. Clinicians should weigh potential benefits against risks and consider alternative therapies when treating pregnant or nursing patients.
How do I order Paracetamolo Kabi from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.
How does Paracetamolo Kabi compare with other analgesic options?+
Compared with oral paracetamol, the intravenous form delivers the drug directly into the bloodstream, achieving faster onset of action and reliable plasma concentrations, which is advantageous in patients unable to take oral medication. It differs from NSAIDs by lacking significant anti‑inflammatory activity and having a lower risk of gastrointestinal irritation.
What are the storage and handling requirements for Paracetamolo Kabi?+
Paracetamolo Kabi must be stored at 2‑8 °C in a refrigerator, protected from light. The solution should not be frozen or shaken. Before use, inspect the vial for particulate matter or discoloration and allow it to reach room temperature if required for administration.
How is Paracetamolo Kabi administered?+
The product is given by intravenous infusion under the supervision of qualified healthcare personnel. The infusion rate and total volume are set according to the prescriber’s instructions, typically using a calibrated infusion pump to ensure accurate delivery.
What are the most serious risks associated with Paracetamolo Kabi?+
Serious risks include anaphylactic reactions, severe hepatic injury especially with overdose, and rare dermatologic conditions such as Stevens‑Johnson syndrome. Prompt recognition of these events and immediate medical intervention are essential.
Who should not receive Paracetamolo Kabi?+
Paracetamolo Kabi should be avoided in patients with known hypersensitivity to paracetamol or any component of the formulation, in individuals with severe hepatic impairment, and in those for whom the risk of serious adverse reactions outweighs the therapeutic benefit.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Paracetamol
Route
Intravenous Use
Manufacturer
Fresenius Kabi Italia S.R.L.
Origin
EU

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