Europe — EMA
Paracetamol Zentiva K.S.
GNH USA supplies Paracetamol Zentiva K.S. (Paracetamol), a non‑opioid analgesic for pain relief and fever reduction. Request a quote for global supply.
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What is Paracetamol?
Paracetamol, the active ingredient in Paracetamol Zentiva K.S., is a non‑opioid analgesic and antipyretic presented as a tablet for oral use. It is commonly used to relieve mild to moderate pain and reduce fever in adults and children.
GNH USA supplies Paracetamol Zentiva K.S. as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol used for?
Paracetamol Zentiva K.S. acts on pain‑related pathways and fever mechanisms in the body. - Headache: provides relief from mild to moderate headache pain. - Fever: reduces elevated body temperature associated with infection or inflammation. - Musculoskeletal pain: eases aches and pains in muscles, joints and back. - Dental pain: alleviates discomfort following dental procedures or toothache. - Cold and flu symptoms: helps control fever and body‑ache discomfort during viral upper‑respiratory infections.
What are the side effects of Paracetamol?
Paracetamol is generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: mild stomach upset that may occur after dosing. - Rash: skin redness or mild itching. - Elevated liver enzymes: transient increase detected in blood tests. - Headache: paradoxical headache in a small number of users.
Serious or Rare Side Effects: - Hepatotoxicity: liver injury that can be severe with overdose or chronic high‑dose use. - Stevens‑Johnson syndrome: rare severe skin reaction. - Anaphylaxis: immediate hypersensitivity reaction requiring emergency care. - Blood disorders: rare cases of thrombocytopenia or neutropenia.
What precautions apply to Paracetamol?
Paracetamol should be used with awareness of specific safety considerations. - Dose limits: do not exceed the maximum daily amount recommended for adults. - Liver disease: avoid use or seek medical advice if you have existing liver impairment. - Alcohol use: limit alcohol consumption while taking this medication. - Pregnancy: consult a healthcare professional before use during pregnancy. - Children: ensure age‑appropriate dosing and formulation. - Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.
What does Paracetamol interact with?
Paracetamol can interact with several medicines, altering its effectiveness or safety profile.
Major Interactions (Avoid): - Warfarin: may increase bleeding risk through enhanced anticoagulant effect. - Isoniazid: can raise the risk of liver toxicity.
Moderate Interactions (Monitor Closely): - Antiepileptic drugs (e.g., carbamazepine, phenytoin): may reduce paracetamol plasma levels. - Rifampicin: increases metabolic clearance, potentially lowering efficacy. - Oral contraceptives: may slightly increase hepatotoxic risk. - High‑dose vitamin C: can affect metabolism and raise liver‑enzyme levels.
