Europe — EMA
Paracetamol Us Pharmacia
GNH USA supplies Paracetamol Us Pharmacia (Paracetamol), an analgesic/antipyretic for fever and mild to moderate pain. Request a quote for global supply.
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What is Paracetamol?
Paracetamol, the active ingredient in Paracetamol Us Pharmacia, is an analgesic/antipyretic presented as a 500 mg tablet for oral use. It relieves mild to moderate pain and reduces fever in adults and children.
GNH USA supplies Paracetamol Us Pharmacia as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol used for?
Paracetamol acts as an analgesic and antipyretic across several common conditions.
- Fever: reduces elevated body temperature. - Headache: alleviates mild to moderate headache pain. - Musculoskeletal pain: provides relief from minor muscle aches and back pain. - Toothache: eases dental pain associated with mild inflammation.
What are the side effects of Paracetamol?
Paracetamol is generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: mild stomach upset experienced by some users. - Abdominal discomfort: occasional stomach pain or indigestion. - Headache: paradoxical headache in rare cases. - Dizziness: transient light‑headedness. - Skin rash: mild itching or erythema.
Serious or Rare Side Effects: - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Hepatotoxicity: liver injury, especially with overdose or chronic high‑dose use. - Blood disorders: agranulocytosis or thrombocytopenia. - Anaphylaxis: rare severe allergic response. - Renal impairment: acute kidney injury in susceptible individuals.
What precautions apply to Paracetamol?
Paracetamol should be used with awareness of specific safety considerations.
- Liver function: avoid use in patients with severe hepatic impairment. - Alcohol consumption: limit intake as combined use increases hepatotoxic risk. - Maximum daily dose: do not exceed the recommended total daily amount. - Pregnancy and breastfeeding: use only if clearly needed after professional assessment. - Pediatric use: ensure appropriate formulation and dosing for children. - Drug interactions: review all concurrent medications for potential interactions. - Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.
What does Paracetamol interact with?
Paracetamol can interact with several medicines, requiring attention to avoid adverse outcomes.
Major Interactions (Avoid): - Other paracetamol‑containing products: risk of cumulative overdose. - Warfarin: may enhance anticoagulant effect and increase bleeding risk. - Strong CYP450 inducers (e.g., rifampicin): may reduce paracetamol efficacy.
Moderate Interactions (Monitor Closely): - Alcohol: additive hepatotoxic potential. - Isoniazid: increased risk of liver injury. - Carbamazepine: may increase paracetamol metabolism, lowering plasma levels. - Antiepileptics (e.g., phenytoin): may alter hepatic enzyme activity. - Certain antivirals: potential for altered clearance.



