GNH USA

Europe — EMA

Paracetamol + Tiocolquicosido Azevedos (Paracetamol, Thiocolchicoside)

GNH USA supplies Paracetamol + Thiocolchicoside (Paracetamol), an analgesic/antipyretic for pain and fever relief. Request a quote for global supply.

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What is Paracetamol, Thiocolchicoside?

Paracetamol, the active ingredient in Paracetamol + Thiocolchicoside, is an analgesic/antipyretic presented as an oral tablet for systemic use. It relieves mild to moderate pain and reduces fever in adults and children. Thiocolchicoside, also present, acts as a skeletal muscle relaxant that helps ease muscle spasm associated with acute musculoskeletal discomfort.

GNH USA supplies Paracetamol + Thiocolchicoside as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Paracetamol, Thiocolchicoside used for?

Paracetamol + Thiocolchicoside combines analgesic and muscle‑relaxant actions to address pain‑related conditions and associated muscle tension.

- Acute musculoskeletal pain: provides pain relief while reducing muscle spasm. - Fever: lowers elevated body temperature in febrile states. - Muscle spasm: relaxes skeletal muscles to improve mobility and comfort.

What are the side effects of Paracetamol, Thiocolchicoside?

Paracetamol + Thiocolchicoside may cause a range of adverse reactions, from mild to serious.

Common Side Effects: - Nausea: mild gastrointestinal upset. - Dizziness: transient light‑headedness. - Headache: occasional tension‑type headache. - Dry mouth: reduced salivation. - Drowsiness: mild sedation. - Gastro‑intestinal discomfort: mild abdominal pain.

Serious or Rare Side Effects: - Allergic reactions: rash, pruritus, or angioedema. - Hepatotoxicity: elevated liver enzymes or liver injury. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Blood disorders: leukopenia or thrombocytopenia. - Seizures: rare central nervous system excitation. - Anaphylaxis: life‑threatening hypersensitivity.

What precautions apply to Paracetamol, Thiocolchicoside?

When using Paracetamol + Thiocolchicoside, consider the following safety measures.

- Liver function monitoring: avoid use in patients with severe hepatic impairment. - Alcohol avoidance: limit alcohol intake to reduce liver risk. - Age restriction: not recommended for children under 12 years without medical supervision. - Renal caution: adjust use in severe renal dysfunction. - Pregnancy and lactation: consult a healthcare professional before use. - Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

What does Paracetamol, Thiocolchicoside interact with?

Paracetamol + Thiocolchicoside can interact with several medicines; some require avoidance while others need close monitoring.

Major Interactions (Avoid): - Alcohol: increases risk of hepatotoxicity. - Warfarin: may enhance anticoagulant effect and bleeding. - Carbamazepine: induces metabolism, reducing efficacy. - Other hepatotoxic drugs: combined liver stress. - Central nervous system depressants: excessive sedation.

Moderate Interactions (Monitor Closely): - CYP450 substrates: possible altered plasma levels. - Antihistamines: may increase drowsiness. - Antidepressants: monitor for serotonin syndrome. - NSAIDs: additive gastrointestinal irritation. - Oral contraceptives: potential reduction in effectiveness.

Frequently asked questions

What is Paracetamol + Thiocolchicoside used for?+
Paracetamol + Thiocolchicoside is a fixed‑dose oral tablet that combines an analgesic/antipyretic with a skeletal muscle relaxant. It is used to relieve mild to moderate pain, reduce fever, and ease associated muscle spasm in conditions such as acute musculoskeletal discomfort.
How does Paracetamol work in this combination?+
Paracetamol acts centrally by inhibiting cyclo‑oxygenase enzymes, which lowers prostaglandin production in the brain and resets the hypothalamic temperature set‑point. This results in analgesia and antipyresis, helping to alleviate pain and fever.
What is the usual dose of Paracetamol + Thiocolchicoside?+
The specific dose and dosing schedule are determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and other medications. Patients should follow the prescriber’s instructions and not exceed the recommended amount.
Is Paracetamol + Thiocolchicoside safe during pregnancy or breastfeeding?+
Safety in pregnancy and lactation has not been fully established. Healthcare providers should evaluate the risk‑benefit ratio before prescribing to pregnant or nursing women, and patients should discuss any concerns with their doctor.
How do I order Paracetamol + Thiocolchicoside from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does this product compare with other pain‑relief options?+
Compared with single‑ingredient analgesics, the combination adds a muscle‑relaxant component, which can be advantageous when pain is accompanied by spasm. Unlike opioid analgesics, it does not carry a risk of dependence, but it lacks the potency of stronger narcotics for severe pain.
What are the storage and handling requirements?+
Paracetamol + Thiocolchicoside tablets should be stored at room temperature, below 25 °C, in the original packaging to protect from moisture and light. Keep the container tightly closed and out of reach of children.
How is the medication administered?+
The tablet is taken orally with a full glass of water. It may be taken with or without food, but patients should follow the prescriber’s guidance regarding timing relative to meals.
What are the most serious risks to watch for?+
Serious risks include signs of liver injury such as jaundice or dark urine, severe allergic reactions like rash or swelling, and rare skin conditions such as Stevens‑Johnson syndrome. Any of these symptoms require immediate medical attention.
Who should not use Paracetamol + Thiocolchicoside?+
Patients with known hypersensitivity to paracetamol, thiocolchicoside, or any excipients should avoid the product. It is also contraindicated in individuals with severe hepatic impairment, uncontrolled hypertension, or those taking medications that strongly interact as listed under major interactions.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Paracetamol, Thiocolchicoside
Route
Oral Use
Manufacturer
Laboratórios Azevedos - Indústria Farmacêutica, S.A.
Origin
EU

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