Europe — EMA
Paracetamol Tecnigen
GNH USA supplies Paracetamol Tecnigen (Paracetamol), an analgesic/antipyretic for fever, headache and mild to moderate pain.
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What is Paracetamol?
Paracetamol, the active ingredient in Paracetamol Tecnigen, is an analgesic presented as an oral tablet for oral use. It is used to relieve mild to moderate pain and to reduce fever in adults and children when appropriate.
GNH USA supplies Paracetamol Tecnigen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol used for?
Paracetamol acts as an analgesic and antipyretic, reducing pain and fever through central mechanisms. - Fever: lowers elevated body temperature in acute and chronic febrile states. - Headache: provides relief from tension‑type and migraine‑associated headache pain. - Musculoskeletal pain: eases mild to moderate pain from strains, sprains, and backache. - Dental pain: reduces discomfort following dental procedures or toothache. - Osteoarthritis: alleviates pain associated with degenerative joint disease.
What are the side effects of Paracetamol?
Paracetamol is generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: mild stomach upset after ingestion. - Rash: skin redness or mild itching. - Abdominal discomfort: occasional stomach pain. - Sweating: increased perspiration. - Headache: paradoxical headache in some users. - Dizziness: transient light‑headedness.
Serious or Rare Side Effects: - Stevens‑Johnson syndrome: severe skin reaction requiring immediate medical attention. - Hepatic failure: rare but potentially fatal liver injury, especially with overdose. - Blood disorders: agranulocytosis or thrombocytopenia. - Severe skin reactions: toxic epidermal necrolysis. - Anaphylaxis: acute allergic response with breathing difficulty. - Hypersensitivity: systemic allergic manifestations.
What precautions apply to Paracetamol?
Paracetamol should be used with attention to safety considerations. - Liver function: assess hepatic health before prolonged use. - Alcohol consumption: avoid or limit alcohol to reduce liver risk. - Dose minimization: use the lowest effective dose for the shortest duration. - Renal impairment: monitor kidney function in patients with chronic kidney disease. - Pregnancy and breastfeeding: limit use to essential situations after professional advice. - Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.
What does Paracetamol interact with?
Paracetamol can interact with several medicines, influencing efficacy or safety.
Major Interactions (Avoid): - Warfarin: increased anticoagulant effect, risk of bleeding. - Carbamazepine: enhanced hepatic metabolism, reducing analgesic effect. - Phenytoin: induces metabolism, lowering plasma levels. - Isoniazid: combined hepatotoxic potential. - Alcohol: synergistic liver toxicity.
Moderate Interactions (Monitor Closely): - Oral contraceptives: may reduce contraceptive efficacy. - Antihypertensives: occasional blood pressure changes. - Other antiepileptics: additive hepatic enzyme induction. - Hepatotoxic drugs: cumulative liver stress. - Lithium: possible alteration of lithium levels.



