Europe — EMA
Paracetamol Sandoz
GNH USA supplies Paracetamol Sandoz (Paracetamol), a analgesic/antipyretic for pain relief and fever reduction. Request a quote for global supply today.
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What is Paracetamol?
Paracetamol, the active ingredient in Paracetamol Sandoz, is an analgesic presented as a 500 mg tablet for oral use. It is used to relieve mild to moderate pain and to reduce fever in adults and children. GNH USA supplies Paracetamol Sandoz as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol used for?
Paracetamol acts systemically to lower temperature and alleviate pain across several common conditions.
Fever: reduces elevated body temperature caused by infection or inflammation. Headache: provides relief from tension‑type and mild migraine headaches. Musculoskeletal pain: eases aches associated with back strain, sprains or arthritis. Dental pain: helps control discomfort after dental procedures. Post‑operative pain: mitigates mild pain following minor surgery.
What are the side effects of Paracetamol?
Paracetamol is generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea or upset stomach. - Mild skin rash or itching. - Transient elevation of liver enzymes. - Headache. - Dizziness. - Sweating.
Serious or Rare Side Effects: - Acute liver failure, especially with overdose. - Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Blood disorders such as thrombocytopenia. - Severe allergic reactions (anaphylaxis). - Hepatic necrosis. - Hypersensitivity reactions with facial swelling.
What precautions apply to Paracetamol?
Paracetamol should be used with attention to patient‑specific factors. - Assess liver function: avoid in severe hepatic impairment. - Limit alcohol intake: concurrent use increases hepatotoxic risk. - Observe maximum daily dose: do not exceed recommended total amount. - Use with caution in renal impairment: monitor kidney function. - Pregnancy and breastfeeding: consult a healthcare professional before use. - Store at room temperature: keep in the original pack, protect from moisture.
What does Paracetamol interact with?
Paracetamol can interact with several medicines, requiring vigilance.
Major Interactions (Avoid): - Alcohol: synergistic hepatotoxicity. - Warfarin: may enhance anticoagulant effect, increasing bleeding risk. - Carbamazepine: enzyme induction can reduce paracetamol efficacy.
Moderate Interactions (Monitor Closely): - Isoniazid: combined use may raise liver enzyme levels. - Oral contraceptives: may modestly increase hepatic enzyme activity. - Antiepileptic drugs (e.g., phenytoin): may alter metabolism, requiring dose review.
