Europe — EMA
Paracetamol Sameko
GNH USA supplies Paracetamol Sameko (Paracetamol), an analgesic/antipyretic for pain relief and fever reduction. Request a quote for global supply today.
Request sourcing
What is Paracetamol?
Paracetamol, the active ingredient in Paracetamol Sameko, is an analgesic presented as an oral formulation for systemic use. It provides pain relief and fever reduction in adults and children.
GNH USA supplies Paracetamol Sameko as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol used for?
Paracetamol is an analgesic‑antipyretic that acts on the central nervous system to relieve pain and reduce fever.
- Mild to moderate pain: provides relief of headaches, musculoskeletal discomfort and dental pain. - Fever: lowers elevated body temperature in infections and inflammatory conditions. - Post‑operative discomfort: helps manage pain after minor surgical procedures.
What are the side effects of Paracetamol?
Paracetamol may cause adverse reactions, which are categorized by frequency.
Common Side Effects: - Nausea: mild stomach upset that usually resolves without intervention. - Skin rash: occasional mild erythema or itching. - Elevated liver enzymes: transient increase detectable in blood tests. - Headache: rare occurrence of mild headache. - Dizziness: occasional light‑headed sensation.
Serious or Rare Side Effects: - Severe liver injury: possible with overdose or chronic high‑dose use. - Allergic anaphylaxis: rare but potentially life‑threatening reaction. - Blood disorders: very rare cases of agranulocytosis or thrombocytopenia.
What precautions apply to Paracetamol?
When using Paracetamol Sameko, consider the following precautions. - Dose limitation: do not exceed the recommended daily maximum to avoid hepatotoxicity. - Alcohol use: avoid excessive alcohol consumption while taking the product. - Liver disease: use only under medical supervision in patients with hepatic impairment. - Renal impairment: monitor kidney function in patients with reduced renal clearance. - Pregnancy and breastfeeding: consult a healthcare professional before use. - Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.
What does Paracetamol interact with?
Paracetamol can interact with other medicines; interactions are grouped by clinical significance.
Major Interactions (Avoid): - Strong CYP2E1 inducers (e.g., rifampicin): may increase hepatotoxic risk. - Chronic high‑dose alcohol use: elevates risk of liver injury. - Concomitant use of other hepatotoxic agents: may compound liver damage.
Moderate Interactions (Monitor Closely): - Warfarin: may enhance anticoagulant effect, requiring INR monitoring. - Isoniazid: may increase liver enzyme levels, necessitating periodic liver function tests. - Carbamazepine: may reduce analgesic efficacy of paracetamol.



