Europe — EMA
Paracetamol Plus Optipharma (Paracetamol, Caffeine)
GNH USA supplies Paracetamol Plus Optipharma (Paracetamol), an analgesic/antipyretic for pain and fever. Request a quote for global supply.
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What is Paracetamol, Caffeine?
Paracetamol, the active ingredient in Paracetamol Plus Optipharma, is an analgesic and antipyretic presented as a tablet for oral use. It treats mild to moderate pain and fever in adults and children. GNH USA supplies Paracetamol Plus Optipharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
GNH USA supplies Paracetamol Plus Optipharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol, Caffeine used for?
Paracetamol Plus Optipharma is used for pain relief and fever reduction across several common conditions.
- Headache: alleviates pain associated with tension‑type and mild migraine headaches. - Fever: reduces elevated body temperature in febrile illnesses. - Musculoskeletal pain: eases mild to moderate aches from strains, sprains and back pain. - Dental pain: provides relief after dental procedures or toothache. - Cold and flu symptoms: helps control headache and fever that accompany viral upper‑respiratory infections.
What are the side effects of Paracetamol, Caffeine?
Paracetamol Plus Optipharma is generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: mild stomach upset that may occur after dosing. - Insomnia: difficulty falling or staying asleep, related to caffeine content. - Headache: paradoxical headache in a minority of users. - Gastro‑intestinal discomfort: mild abdominal pain or dyspepsia.
Serious or Rare Side Effects: - Allergic reaction: rash, itching, swelling, or difficulty breathing. - Hepatotoxicity: elevated liver enzymes or liver injury, especially with overdose. - Cardiovascular effects: palpitations or rapid heart rate. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
What precautions apply to Paracetamol, Caffeine?
Paracetamol Plus Optipharma should be used with awareness of specific safety considerations.
- Liver function: avoid use in patients with severe hepatic impairment or chronic liver disease. - Pregnancy: limit use to the lowest effective dose and only when clearly needed. - Caffeine sensitivity: caution in individuals prone to anxiety, insomnia or arrhythmias. - Drug interactions: review concomitant medications for potential additive effects. - Alcohol use: limit alcohol consumption as it may increase liver risk. - Store at ambient temperature: keep below 25°C, retain in original packaging, protect from moisture.
What does Paracetamol, Caffeine interact with?
Paracetamol Plus Optipharma can interact with several medicines; monitoring is advised.
Major Interactions (Avoid): - Warfarin: increased anticoagulant effect may raise bleeding risk. - Highly hepatotoxic drugs: combined liver stress can precipitate injury.
Moderate Interactions (Monitor Closely): - CYP1A2 substrates (e.g., theophylline): caffeine may raise plasma levels. - Antiepileptic drugs (e.g., carbamazepine): may reduce paracetamol clearance. - Diuretics: potential for altered electrolyte balance with caffeine. - MAO inhibitors: possible enhancement of stimulant effects. - NSAIDs: additive gastrointestinal irritation risk.



