Europe — EMA
Paracetamol Ovaal Kruidvat
GNH USA supplies Paracetamol Ovaal Kruidvat (Paracetamol), a non‑opioid analgesic for pain relief and fever reduction. Request a quote for global supply.
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What is Paracetamol?
Paracetamol, the active ingredient in Paracetamol Ovaal Kruidvat, is a non‑opioid analgesic and antipyretic presented as a tablet for oral use. It is commonly used to relieve mild to moderate pain and reduce fever in adults and children.
GNH USA supplies Paracetamol Ovaal Kruidvat as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.
What is Paracetamol used for?
Paracetamol acts as an analgesic and antipyretic across several common conditions: - Headache: provides relief from mild to moderate pain associated with tension‑type or migraine onset. - Fever: reduces elevated body temperature in viral or bacterial infections. - Musculoskeletal pain: eases discomfort from strains, sprains and minor joint aches. - Dental pain: alleviates pain following dental procedures or toothache. - Menstrual cramps: helps lessen cramping discomfort during menstruation.
What are the side effects of Paracetamol?
Paracetamol is generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: mild stomach upset that may occur after dosing. - Rash: transient skin redness or itching. - Elevated liver enzymes: mild, reversible changes in liver function tests.
Serious or Rare Side Effects: - Hepatotoxicity: severe liver injury, especially with overdose or chronic high‑dose use. - Stevens‑Johnson syndrome: rare severe skin reaction. - Anaphylaxis: immediate hypersensitivity requiring emergency care. - Blood disorders: rare cases of agranulocytosis or thrombocytopenia.
What precautions apply to Paracetamol?
Paracetamol should be used with awareness of several safety considerations: - Liver function: avoid use in patients with severe hepatic impairment or active liver disease. - Alcohol consumption: limit intake as combined use increases risk of liver injury. - Concomitant medications: review other products containing paracetamol to prevent accidental overdose. - Pregnancy and lactation: use only under medical advice, especially in the third trimester. - Children: ensure appropriate dose form and strength for age and weight. - Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.
What does Paracetamol interact with?
Paracetamol can interact with other medicines, requiring attention to dosage and monitoring:
Major Interactions (Avoid): - Warfarin: increased anticoagulant effect may raise bleeding risk. - Isoniazid: combined use can enhance hepatotoxic potential.
Moderate Interactions (Monitor Closely): - Antiepileptics (e.g., carbamazepine, phenytoin): may reduce paracetamol plasma levels. - HIV protease inhibitors: potential alteration of metabolism increasing toxicity risk. - Oral contraceptives: may slightly increase hepatic enzyme activity affecting drug clearance.



