GNH USA

Europe — EMA

Migränerton (Paracetamol, Metoclopramide Hydrochloride Monohydrate)

GNH USA supplies Migränerton (Paracetamol/Metoclopramide), a combined analgesic and antiemetic for migraine and related nausea. Request a quote for supply.

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What is Paracetamol, Metoclopramide Hydrochloride Monohydrate?

Paracetamol and Metoclopramide Hydrochloride Monohydrate, the active ingredients in Migränerton, are analgesic and antiemetic agents presented as an oral tablet for oral use. They are employed to relieve migraine pain and associated nausea in adult patients. GNH USA supplies Migränerton as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Paracetamol, Metoclopramide Hydrochloride Monohydrate used for?

Migränerton combines an analgesic and an antiemetic to address migraine and its related symptoms.

Migraine: alleviates headache pain and reduces associated nausea. Headache: provides relief of moderate pain intensity. Nausea associated with migraine: controls vomiting and improves comfort.

What are the side effects of Paracetamol, Metoclopramide Hydrochloride Monohydrate?

Common Side Effects: - Drowsiness or fatigue. - Dry mouth. - Mild gastrointestinal discomfort. - Dizziness. - Transient visual disturbances.

Serious or Rare Side Effects: - Extrapyramidal reactions such as dystonia or akathisia. - Severe allergic reactions including rash, itching, or swelling. - Elevated liver enzymes or hepatic dysfunction. - Neuroleptic malignant syndrome (very rare). - Persistent vomiting or severe gastrointestinal upset.

What precautions apply to Paracetamol, Metoclopramide Hydrochloride Monohydrate?

Before using Migränerton, consider the following precautions.

Avoid use in patients with known hypersensitivity to paracetamol or metoclopramide. Monitor liver function in individuals with hepatic impairment. Use caution in patients with a history of movement disorders or Parkinsonian symptoms. Do not combine with other dopamine‑blocking agents without medical advice. Store at ambient temperature below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

What does Paracetamol, Metoclopramide Hydrochloride Monohydrate interact with?

Migränerton may interact with several medicines; awareness of these interactions helps ensure safety.

Major Interactions (Avoid): - Monoamine oxidase inhibitors (MAOIs): risk of severe hypertension. - Other dopamine antagonists: increased risk of extrapyramidal symptoms. - High‑dose paracetamol products: potential liver toxicity.

Moderate Interactions (Monitor Closely): - Anticoagulants (e.g., warfarin): may enhance anticoagulant effect. - CYP450‑metabolized drugs (e.g., carbamazepine): possible alteration of plasma levels. - Alcohol consumption: may increase hepatotoxic risk.

Frequently asked questions

What is Migränerton used for?+
Migränerton is indicated for the treatment of migraine attacks, including relief of headache pain and associated nausea. It is also used for other types of headache where an analgesic and antiemetic combination is appropriate.
How does Paracetamol work in Migränerton?+
Paracetamol provides analgesic and antipyretic effects by centrally inhibiting the synthesis of prostaglandins, which are mediators of pain and fever. This action helps reduce the intensity of migraine‑related head pain.
What is the usual dose of Migränerton?+
The dosage of Migränerton is determined by the prescribing healthcare professional based on the patient’s clinical condition, age, and response to therapy. Patients should follow the prescriber’s instructions and not exceed the recommended amount.
Is Migränerton safe during pregnancy or breastfeeding?+
Safety data for Migränerton in pregnancy and lactation are limited. The prescriber should evaluate the potential benefits against any possible risks before prescribing to pregnant or nursing mothers.
How do I order Migränerton from GNH USA?+
To order Migränerton, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.
How does Migränerton compare with other migraine treatments?+
Migränerton combines an analgesic (paracetamol) with an antiemetic (metoclopramide), offering simultaneous headache and nausea relief. Unlike triptans, which target serotonin receptors, this combination is useful when nausea is prominent or when triptans are contraindicated.
What are the storage requirements for Migränerton?+
Store Migränerton at ambient temperature below 25 °C. Keep the tablets in the original container, protect them from moisture, heat and direct sunlight to maintain stability.
How is Migränerton administered?+
Migränerton is taken orally, usually with a glass of water. It should be swallowed whole and not chewed or crushed, unless otherwise directed by a healthcare professional.
What are the most serious risks associated with Migränerton?+
Serious risks include extrapyramidal reactions such as dystonia, severe allergic reactions, and rare hepatic injury. Patients should seek immediate medical attention if they experience muscle rigidity, rash, swelling, or signs of liver dysfunction.
Who should not use Migränerton?+
Migränerton should be avoided in individuals with known hypersensitivity to paracetamol or metoclopramide, those with severe liver disease, or patients with a history of movement disorders such as Parkinson’s disease.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Paracetamol, Metoclopramide Hydrochloride Monohydrate
Route
Oral Use
Manufacturer
Esteve Pharmaceuticals Gmbh
Origin
EU

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