Europe — EMA
Migränerton (Paracetamol, Metoclopramide Hydrochloride Monohydrate)
GNH USA supplies Migränerton (Paracetamol/Metoclopramide), a combined analgesic and antiemetic for migraine and related nausea. Request a quote for supply.
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What is Paracetamol, Metoclopramide Hydrochloride Monohydrate?
Paracetamol and Metoclopramide Hydrochloride Monohydrate, the active ingredients in Migränerton, are analgesic and antiemetic agents presented as an oral tablet for oral use. They are employed to relieve migraine pain and associated nausea in adult patients. GNH USA supplies Migränerton as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol, Metoclopramide Hydrochloride Monohydrate used for?
Migränerton combines an analgesic and an antiemetic to address migraine and its related symptoms.
Migraine: alleviates headache pain and reduces associated nausea. Headache: provides relief of moderate pain intensity. Nausea associated with migraine: controls vomiting and improves comfort.
What are the side effects of Paracetamol, Metoclopramide Hydrochloride Monohydrate?
Common Side Effects: - Drowsiness or fatigue. - Dry mouth. - Mild gastrointestinal discomfort. - Dizziness. - Transient visual disturbances.
Serious or Rare Side Effects: - Extrapyramidal reactions such as dystonia or akathisia. - Severe allergic reactions including rash, itching, or swelling. - Elevated liver enzymes or hepatic dysfunction. - Neuroleptic malignant syndrome (very rare). - Persistent vomiting or severe gastrointestinal upset.
What precautions apply to Paracetamol, Metoclopramide Hydrochloride Monohydrate?
Before using Migränerton, consider the following precautions.
Avoid use in patients with known hypersensitivity to paracetamol or metoclopramide. Monitor liver function in individuals with hepatic impairment. Use caution in patients with a history of movement disorders or Parkinsonian symptoms. Do not combine with other dopamine‑blocking agents without medical advice. Store at ambient temperature below 25°C: keep in the original packaging, protect from moisture and direct sunlight.
What does Paracetamol, Metoclopramide Hydrochloride Monohydrate interact with?
Migränerton may interact with several medicines; awareness of these interactions helps ensure safety.
Major Interactions (Avoid): - Monoamine oxidase inhibitors (MAOIs): risk of severe hypertension. - Other dopamine antagonists: increased risk of extrapyramidal symptoms. - High‑dose paracetamol products: potential liver toxicity.
Moderate Interactions (Monitor Closely): - Anticoagulants (e.g., warfarin): may enhance anticoagulant effect. - CYP450‑metabolized drugs (e.g., carbamazepine): possible alteration of plasma levels. - Alcohol consumption: may increase hepatotoxic risk.


