Europe — EMA
Paracetamol Krka
Paracetamol, the active ingredient in Paracetamol Krka, is a analgesic and antipyretic presented as a tablet for oral use. It is commonly used to relieve mild to moderate pain and reduce fever in adults and children.
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What is Paracetamol?
Paracetamol, the active ingredient in Paracetamol Krka, is a analgesic and antipyretic presented as a tablet for oral use. It is commonly used to relieve mild to moderate pain and reduce fever in adults and children.
GNH USA supplies Paracetamol Krka as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol used for?
Paracetamol Krka is used for pain relief and fever reduction by acting on the body's temperature‑regulating pathways. - Headache: alleviates pain associated with tension or migraine onset. - Musculoskeletal pain: reduces discomfort from strains, sprains and minor injuries. - Fever: lowers elevated body temperature in infections or inflammatory conditions.
What are the side effects of Paracetamol?
Paracetamol is generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: mild stomach upset that may occur after dosing. - Skin rash: occasional mild erythema or itching. - Elevated liver enzymes: transient increase detected in routine blood work.
Serious or Rare Side Effects: - Hepatotoxicity: risk of liver injury with overdose or chronic high‑dose use. - Stevens‑Stevenson or Stevens‑Johnson syndrome: severe skin reactions requiring immediate medical attention. - Anaphylaxis: rare allergic reaction with symptoms such as difficulty breathing, swelling and hives. - Blood disorders: rare cases of thrombocytopenia or agranulocytosis.
What precautions apply to Paracetamol?
Paracetamol should be used with awareness of specific safety considerations. - Liver function: avoid use in patients with severe hepatic impairment or active liver disease. - Alcohol consumption: limit intake as concurrent alcohol use may increase liver toxicity risk. - Drug interactions: review concomitant medications for potential CYP450 interactions. - Pregnancy and lactation: use only under medical guidance, weighing potential benefits against risks. - Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.
What does Paracetamol interact with?
Paracetamol may interact with several medicines, requiring monitoring.
Major Interactions (Avoid): - Warfarin: may enhance anticoagulant effect and increase bleeding risk. - High‑dose cocaine or illicit opio ‑ ");
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