GNH USA

Europe — EMA

Paracetamol/Ibuprofene Medipha (Ibuprofen, Paracetamol)

GNH USA supplies Paracetamol/Ibuprofene Medipha (Ibuprofen & Paracetamol), a non‑steroidal anti‑inflammatory and analgesic for pain and fever.

Ibuprofen, Paracetamol

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What is Ibuprofen, Paracetamol?

Ibuprofen, the active ingredient in Paracetamol/Ibuprofene Medipha, is a non‑steroidal anti‑inflammatory drug presented as a combined formulation for oral use. It relieves pain, reduces fever and decreases inflammation in adults and children when used as directed. GNH USA supplies Paracetamol/Ibuprofene Medipha as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Ibuprofen, Paracetamol used for?

Paracetamol/Ibuprofene Medipha combines two well‑known analgesic‑antipyretic agents that act on pain‑related and inflammatory pathways. It is indicated for: - Headache: provides rapid relief of mild to moderate headache pain. - Dental pain: helps control postoperative dental discomfort. - Musculoskeletal pain: reduces inflammation‑associated pain from strains, sprains and low‑back tension. - Fever: lowers elevated body temperature in febrile adults and children. - Minor arthritic pain: eases discomfort from osteoarthritis flares.

What are the side effects of Ibuprofen, Paracetamol?

Paracetamol/Ibuprofene Medipha may cause a range of adverse reactions.

Common Side Effects: - Gastrointestinal discomfort: mild nausea, dyspepsia or heartburn. - Headache: transient worsening of headache. - Dizziness: light‑headed sensation. - Skin reddening: mild flushing. - Elevated liver enzymes: mild, reversible changes in blood tests.

Serious or Rare Side Effects: - Gastrointestinal ulceration or bleeding. - Severe skin reactions such as Stevens‑Johnson syndrome. - Hepatotoxicity: significant liver injury, especially with overdose. - Renal impairment: reduced kidney function or acute failure. - Anaphylaxis: rapid onset of swelling, hives and airway compromise.

What precautions apply to Ibuprofen, Paracetamol?

When using Paracetamol/Ibuprofene Medipha, consider the following safety measures: - Assess renal function: avoid use in severe chronic kidney disease. - Monitor hepatic health: caution in patients with liver disease or chronic alcohol use. - Avoid concurrent NSAID use: reduces risk of gastrointestinal bleeding. - Use lowest effective dose: limit duration to the shortest period needed for symptom control. - Pregnancy and lactation: consult a healthcare professional before use. - Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

What does Ibuprofen, Paracetamol interact with?

Paracetamol/Ibuprofene Medipha can interact with several medicines.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of bleeding. - High‑dose aspirin aspirin: additive gastrointestinal toxicity. - Selective COX‑2 inhibitors (e.g., celecoxib): heightened cardiovascular risk.

Moderate Interactions (Monitor Closely): - ACE inhibitors (e.g., enalapril): may reduce renal perfusion. - Diuretics (e.g., furosemide): potential for reduced kidney function. - Lithium: NSAID component can raise lithium serum levels. - Methotrexate: ibuprofen may delay clearance, increasing toxicity.

Frequently asked questions

What is Paracetamol/Ibuprofene Medipha used for?+
Paracetamol/Ibuprofene Medipha is a combined oral formulation of ibuprofen and paracetamol that provides analgesic, antipyretic and anti‑inflammatory effects. It is commonly used to relieve mild‑to‑moderate pain such as headache, dental or musculoskeletal pain, and to reduce fever in adults and children when prescribed by a healthcare professional.
How does ibuprofen work in this product?+
Ibuprofen blocks cyclo‑oxygenase‑1 and cyclo‑oxygenase‑2 enzymes, which reduces the production of prostaglandins that cause inflammation, pain and fever. The reduction of prostaglandins lessens the sensitisation of nerve endings and lowers body temperature, contributing to the overall symptom relief of the combination product.
What is the usual dose of Paracetamol/Ibuprofene Medipha?+
The specific dose and dosing interval are determined by the prescribing clinician based on the patient’s age, weight, clinical condition and any concomitant therapies. Healthcare providers set the appropriate regimen and should follow local prescribing guidelines.
Is Paracetamol/Ibuprofene Medipha safe during pregnancy or breastfeeding?+
Safety in pregnancy and lactation depends on the trimester and individual risk factors. Ibuprofen is generally avoided in the third trimester, while paracetamol is considered relatively safe when used at recommended doses. Clinicians should evaluate the benefit‑risk balance before prescribing to pregnant or nursing mothers.
How do I order Paracetamol/Ibuprofene Medipha from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com with the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does this combination compare with using ibuprofen or paracetamol alone?+
The combination offers additive analgesic and antipyretic effects, allowing lower individual doses of each agent while achieving comparable pain relief and fever reduction. This can reduce the risk of dose‑related side effects associated with higher single‑agent dosing, though the safety profile must still be monitored.
What are the storage and handling requirements for Paracetamol/Ibuprofene Medipha?+
Store the product at temperatures below 25 °C in its original packaging. Protect it from moisture, direct sunlight and extreme humidity to maintain potency and prevent degradation.
How is Paracetamol/Ibuprofene Medipha administered?+
The medication is taken orally, usually with a glass of water. It may be taken with or without food, although taking it with food can lessen gastrointestinal discomfort for some patients.
What are the most serious risks associated with this product?+
Serious risks include gastrointestinal bleeding or ulceration, severe skin reactions such as Stevens‑Johnson syndrome, hepatotoxicity especially with overdose, renal impairment and anaphylaxis. Patients should seek immediate medical attention if they notice signs of these conditions.
Who should not use Paracetamol/Ibuprofene Medipha?+
Individuals with known hypersensitivity to ibuprofen, paracetamol or any excipients, those with active peptic ulcer disease, severe liver or kidney impairment, and patients on anticoagulant therapy without close monitoring should avoid this product unless directed by a physician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Ibuprofen, Paracetamol
Route
Oral Use
Manufacturer
Medipha Sante
Origin
EU

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