Europe — EMA
Paracetamol/Ibuprofen Jed (Ibuprofen, Paracetamol)
GNH USA supplies Paracetamol/Ibuprofen Jed (Ibuprofen), a non‑steroidal anti‑inflammatory drug for pain, fever and postoperative inflammation.
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What is Ibuprofen, Paracetamol?
Ibuprofen, the active ingredient in Paracetamol/Ibuprofen Jed, is a non‑steroidal anti‑inflammatory drug presented as a combination formulation for intravenous use. It is employed to manage pain and fever in hospital settings. GNH USA supplies Paracetamol/Ibuprofen Jed as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.
GNH USA supplies Paracetamol/Ibuprofen Jed as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.
What is Ibuprofen, Paracetamol used for?
Paracetamol/Ibuprofen Jed combines two analgesic agents that act on inflammatory and temperature‑regulation pathways.
- Pain relief: Provides short‑term reduction of moderate to severe pain following surgery or trauma. - Fever reduction: Lowers elevated body temperature in acute febrile states. - Inflammatory control: Helps control postoperative inflammation and associated discomfort.
What are the side effects of Ibuprofen, Paracetamol?
Paracetamol/Ibuprofen Jed may cause a range of adverse reactions.
Common Side Effects: - Nausea - Headache - Dizziness - Injection site pain - Mild elevation of liver enzymes
Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis) - Gastrointestinal bleeding or ulceration - Acute kidney injury - Hepatotoxicity - Stevens‑Stevenson disease
What precautions apply to Ibuprofen, Paracetamol?
When using Paracetamol/Ibuprofen Jed, several safety considerations are recommended.
- Renal function monitoring: Assess baseline and periodic kidney function, especially in patients with pre‑existing renal impairment. - Hepatic monitoring: Check liver enzymes before and during therapy in patients with liver disease. - Cardiovascular risk: Use cautiously in patients with hypertension or cardiovascular disease. - Concomitant NSAID use: Avoid combining with other NSAIDs or high‑dose aspirin to reduce gastrointestinal risk. - Pregnancy and lactation: Use only if clearly indicated and benefits outweigh risks. - Store at ambient temperature: keep in the original packaging, protect from moisture and light.
What does Ibuprofen, Paracetamol interact with?
Paracetamol/Ibuprofen Jed can interact with several medicines, requiring attention to avoid reduced efficacy or increased toxicity.
Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): Heightened bleeding risk. - High‑dose aspirin or other NSAIDs: Increased gastrointestinal toxicity. - Lithium: Ibuprofen may raise serum lithium levels.
Moderate Interactions (Monitor Closely): - ACE inhibitors (e.g., enalapril): May diminish antihypertensive effect. - Diuretics (e.g., furosemide): Potential for reduced renal clearance. - Methotrexate: Ibuprofen can decrease renal elimination, raising toxicity risk.
