Europe — EMA
Paracetamol Hexal
GNH USA supplies Paracetamol Hexal (Paracetamol), an analgesic/antipyretic for pain relief and fever reduction. Request a quote for global supply.
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What is Paracetamol?
Paracetamol, the active ingredient in Paracetamol Hexal, is an analgesic presented as a 500 mg tablet for oral use. It relieves mild to moderate pain and reduces fever in adults and children. GNH USA supplies Paracetamol Hexal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
GNH USA supplies Paracetamol Hexal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol used for?
Paracetamol acts on the prostaglandin pathway to provide analgesic and antipyretic effects.
- Headache: reduces pain intensity and improves comfort. - Fever: lowers elevated body temperature. - Mild to moderate musculoskeletal pain: eases discomfort associated with strains, sprains and backache. - Dental pain: alleviates pain following dental procedures. - Common cold symptoms: helps control fever and headache associated with viral upper respiratory infections.
What are the side effects of Paracetamol?
Paracetamol is generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: occasional mild stomach upset. - Skin rash: transient erythema or mild itching. - Elevated liver enzymes: mild, reversible changes in liver function tests.
Serious or Rare Side Effects: - Stevens‑Johnson syndrome: severe skin reaction requiring immediate medical attention. - Acute liver failure: risk increases with overdose or chronic high‑dose use. - Hypersensitivity anaphylaxis: rare but potentially life‑threatening allergic reaction. - Blood disorders: rare cases of thrombocytopenia or neutropenia. - Renal impairment: uncommon renal function decline in susceptible individuals.
What precautions apply to Paracetamol?
Paracetamol should be used with awareness of specific safety considerations.
- Dose limitation: do not exceed the maximum daily amount recommended by a healthcare professional. - Liver disease: avoid use or adjust dose in patients with hepatic impairment. - Alcohol consumption: limit intake as alcohol can increase hepatotoxic risk. - Pregnancy and lactation: use only under medical advice, especially in the first trimester. - Concomitant medications: review all other products containing paracetamol to prevent accidental overdose. - Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.
What does Paracetamol interact with?
Paracetamol may interact with several medicines, requiring attention to dosage and monitoring.
Major Interactions (Avoid): - Warfarin: increased anticoagulant effect may raise bleeding risk.
Moderate Interactions (Monitor Closely): - Isoniazid: combined use can heighten risk of liver toxicity. - Carbamazepine: may reduce paracetamol plasma levels. - Antiepileptic drugs (e.g., phenytoin, phenobarbital): may enhance hepatic metabolism. - Alcohol: synergistic hepatotoxic potential. - Certain herbal‑based supplements: may affect liver enzyme activity.
