Paracetamol Hasco

Paracetamol, the active ingredient in Paracetamol Hasco, is an analgesic presented as a rectal formulation for rectal use. It reduces mild to moderate pain and lowers fever in adults, adolescents, and children, providing symptomatic relief for conditions such as headache, musculoskeletal discomfort, and febrile illnesses.

GNH USA supplies Paracetamol Hasco as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and regulatory requirements to ensure product safety and efficacy across global markets.

Paracetamol is an analgesic and antipyretic used to manage pain and fever.

- Pain: Provides relief of mild to moderate nociceptive pain. - Fever: Reduces elevated body temperature associated with infectious or inflammatory processes. - Headache: Alleviates tension‑type and mild migraine headaches. - Musculoskeletal discomfort: Eases aches from strains, sprains, or over‑exertion. - Dental pain: Controls pain following dental procedures or toothache.

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea: Mild gastrointestinal upset. - Abdominal discomfort: Stomach pain or discomfort. - Rash: Skin redness or mild itching. - Sweating: Increased perspiration. - Dizziness: Light‑headed sensation. - Headache: Persistent mild headache.

Serious or Rare Side Effects: - Hepatotoxicity: Severe liver injury, especially with overdose. - Stevens‑Johnson syndrome: Rare severe skin reaction. - Anaphylaxis: Immediate hypersensitivity reaction. - Blood dyscrasias: Uncommon blood cell abnormalities. - Renal impairment: Kidney function reduction in susceptible individuals. - Severe skin reactions: Toxic epidermal necrolysis.

Paracetamol should be used with caution in certain populations and conditions.

- Assess liver function: Avoid or limit use in patients with severe hepatic disease. - Monitor renal function: Use carefully in individuals with impaired kidney function. - Limit alcohol intake: Reduce risk of liver toxicity when combined with alcohol. - Pregnancy and lactation: Use only if clearly needed and after professional advice. - Pediatric dosing: Ensure appropriate formulation and dosing for children. - Store at ambient temperature: Keep below 25 °C, protect from moisture and direct sunlight.

Paracetamol may interact with other medicines, altering its efficacy or safety.

Major Interactions (Avoid): - Alcohol: Increases risk of hepatotoxicity. - Warfarin: May enhance anticoagulant effect, raising bleeding risk. - Carbamazepine: Induces metabolism, reducing analgesic effect.

Moderate Interactions (Monitor Closely): - Isoniazid: May increase risk of liver injury. - Phenytoin: Can affect drug metabolism. - Oral contraceptives: May slightly reduce contraceptive effectiveness. - Rifampicin: May lower plasma concentrations of paracetamol.