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What is Paracetamol?
Paracetamol, the active ingredient in Paracetamol Fresenius Kabi, is a widely used analgesic and antipyretic presented as a standard oral tablet for systemic use. It is employed to relieve mild to moderate pain and reduce fever in adults and children. GNH USA supplies Paracetamol Fresenius Kabi as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
GNH USA supplies Paracetamol Fresenius Kabi as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol used for?
Paracetamol Fresenius Kabi is used to manage pain and fever across several common clinical situations.
- Headache: provides relief from mild to moderate tension‑type headaches. - Fever: reduces elevated body temperature associated with infections. - Musculoskeletal pain: eases discomfort from strains, sprains and minor injuries. - Dental pain: alleviates pain following dental procedures or toothache. - Post‑operative pain: helps control mild pain after minor surgical interventions.
What are the side effects of Paracetamol?
Paracetamol is generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: mild stomach upset may be experienced. - Rash: occasional skin redness or mild itching. - Elevated liver enzymes: transient increase detected in blood tests. - Headache: paradoxical headache in a small number of users.
Serious or Rare Side Effects: - Hepatotoxicity: risk of liver injury with overdose or prolonged high‑dose use. - Stevens‑Johnson syndrome: rare severe skin reaction. - Anaphylaxis: extremely rare allergic response requiring immediate medical attention. - Blood disorders: rare cases of thrombocytopenia or neutropenia.
What precautions apply to Paracetamol?
Paracetamol should be used with awareness of specific safety considerations.
- Dose limitation: adhere to recommended maximum daily dose to avoid liver toxicity. - Alcohol use: limit alcohol consumption as it may increase hepatic risk. - Pre‑existing liver disease: use only under medical supervision. - Pregnancy: consult healthcare provider before use during pregnancy. - Pediatric use: ensure appropriate formulation and dosing for children. - Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.
What does Paracetamol interact with?
Paracetamol may interact with other medicines, requiring attention to avoid reduced efficacy or increased toxicity.
Major Interactions (Avoid): - Warfarin: may enhance anticoagulant effect and increase bleeding risk. - Isoniazid: combined use can raise risk of liver injury.
Moderate Interactions (Monitor Closely): - Antiepileptic drugs (e.g., carbamazepine, phenytoin): may increase metabolism of paracetamol, reducing its effectiveness. - Rifampicin: may lower plasma concentrations of paracetamol. - Alcohol: concurrent use can potentiate hepatotoxic potential. - Certain herbal S
