Europe — EMA
Paracetamol Evolugen Pharma
GNH USA supplies Paracetamol Evolugen Pharma (Paracetamol), an analgesic for pain relief and fever reduction. Request a quote for global supply.
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What is Paracetamol?
Paracetamol, the active ingredient in Paracetamol Evolugen Pharma, is an analgesic presented as a 500 mg tablet for oral use. It relieves mild to moderate pain and reduces fever in adults and children. GNH USA supplies Paracetamol Evolugen Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
GNH USA supplies Paracetamol Evolugen Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol used for?
Paracetamol is used across several common pain‑related pathways and fever mechanisms.
- Headache: provides relief of pain associated with tension‑type and mild migraine episodes. - Fever: reduces elevated body temperature in infectious or inflammatory conditions. - Musculoskeletal pain: eases discomfort from strains, sprains and minor joint aches. - Dental pain: alleviates pain following dental procedures or toothache. - Cold and flu symptoms: helps control headache and fever associated with upper respiratory infections.
What are the side effects of Paracetamol?
Paracetamol is generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: mild stomach upset may be reported. - Rash: occasional skin redness or mild itching. - Elevated liver enzymes: transient increase detected in blood tests.
Serious or Rare Side Effects: - Hepatotoxicity: risk of liver injury, especially with overdose or chronic high‑dose use. - Stevens‑Johnson syndrome: rare severe skin reaction. - Blood disorders: uncommon cases of thrombocytopenia or neutropenia. - Anaphylaxis: extremely rare systemic allergic reaction. - Hypersensitivity reactions: including angio‑edema and urticaria.
What precautions apply to Paracetamol?
When using Paracetamol, consider the following safety measures:
- Dose limitation: do not exceed the maximum daily amount recommended by a healthcare professional. - Liver health: avoid use in patients with severe hepatic impairment or active liver disease. - Alcohol consumption: limit alcohol intake as it may increase hepatotoxic risk. - Concomitant medications: review other products containing paracetamol to prevent accidental overdose. - Pregnancy and lactation: use only under medical advice, weighing potential benefits against risks. - Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.
What does Paracetamol interact with?
Paracetamol may interact with several medicines, requiring attention to dosage and monitoring.
Major Interactions (Avoid): - Warfarin: increased anticoagulant effect may raise bleeding risk. - Isoniazid: combined use can heighten risk of liver toxicity.
Moderate Interactions (Monitor Closely): - Antiepileptic drugs (e.g., carbamazepine, phenytoin): may alter paracetamol metabolism. - Rifampicin: can increase hepatic clearance, reducing analgesic effect. - Oral contraceptives: may slightly elevate liver enzyme activity, affecting drug levels. - High‑dose vitamin C: large amounts may enhance paracetamol’s hepatotoxic potential. - Cimetidine: may reduce clearance, modestly raising plasma concentrations.
