Europe — EMA
Paracetamol Dari Pharma
GNH USA supplies Paracetamol Dari Pharma (Paracetamol), a analgesic/antipyretic for pain and fever.
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What is Paracetamol?
Paracetamol, the active ingredient in Paracetamol Dari Pharma, is an analgesic presented as an oral dosage form for oral use. It reduces pain and fever in adults and children and is available over‑the‑counter in the EU market.
GNH USA supplies Paracetamol Dari Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol used for?
Paracetamol is an analgesic and antipyretic that acts on the prostaglandin pathway to relieve symptoms.
Pain: provides relief of mild to moderate pain such as headache or musculoskeletal discomfort. Fever: lowers elevated body temperature in febrile conditions. Headache: alleviates tension‑type headache. Toothache: eases dental pain after procedures. Muscular aches: reduces soreness associated with minor muscle strain.
What are the side effects of Paracetamol?
Paracetamol is generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea - Abdominal discomfort - Rash or mild skin irritation - Dizziness - Headache - Transient increase in liver enzymes
Serious or Rare Side Effects: - Severe skin reactions such as Stevens‑Johnson syndrome - Acute liver failure, especially with overdose - Blood dyscrasias (e.g., agranulocytosis) - Anaphylactic or severe allergic reactions - Hepatotoxicity in patients with pre‑existing liver disease
What precautions apply to Paracetamol?
When using Paracetamol, consider the following safety measures.
Do not exceed recommended daily dose: follow prescriber or label instructions. Avoid concurrent alcohol consumption: increases risk of liver injury. Use caution in liver disease: assess hepatic function before use. Use caution in renal impairment: dose adjustment may be needed. Use in children only as directed by a healthcare professional. Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.
What does Paracetamol interact with?
Paracetamol may interact with other medicines; monitor accordingly.
Major Interactions (Avoid): - Alcohol: potentiates hepatotoxicity. - Warfarin: may enhance anticoagulant effect. - Carbamazepine: induces metabolism, reducing paracetamol efficacy. - Rifampin: induces hepatic enzymes, lowering plasma levels. - Phenytoin: increases metabolism, decreasing therapeutic effect.
Moderate Interactions (Monitor Closely): - Isoniazid: may increase risk of liver injury. - Phenobarbital: induces metabolism, may reduce effectiveness. - Oral contraceptives: may slightly increase hepatic enzyme activity. - HIV protease inhibitors: can alter paracetamol clearance. - NSAIDs: additive gastrointestinal irritation risk.



