Paracetamol Da

Paracetamol, the active ingredient in Paracetamol Da, is an analgesic presented as a rectal suppository for rectal use. It relieves pain and reduces fever in adults and children as appropriate.

GNH USA supplies Paracetamol Da as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Paracetamol Da is used to manage common pain and fever conditions by acting on the body's prostaglandin pathways. - Pain: provides relief of mild to moderate acute pain such as headache, toothache, or musculoskeletal discomfort. - Fever: lowers elevated body temperature associated with infections or inflammatory states. - Cold‑and‑flu symptoms: helps reduce discomfort and fever that accompany viral upper respiratory infections.

Paracetamol Da may cause adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nausea: mild stomach upset occurring shortly after administration. - Skin rash: transient erythematous rash without systemic involvement. - Dizziness: brief sensation of light‑headedness. - Abdominal discomfort: mild cramping or discomfort in the abdomen.

Serious or Rare Side Effects: - Hepatotoxicity: potential liver injury, especially with overdose or chronic high‑dose use. - Stevens‑Johnson syndrome: rare severe skin reaction requiring immediate medical attention. - Anaphylaxis: extremely rare allergic reaction with airway compromise. - Blood dyscrasias: rare cases of agranulocytosis or thrombocytopenia.

Paracetamol Da should be used with awareness of specific safety considerations. - Dose limitation: adhere to recommended maximum daily dose to avoid liver toxicity. - Alcohol use: limit alcohol consumption as combined use increases hepatic risk. - Pre‑existing liver disease: avoid or use only under medical supervision. - Pregnancy and lactation: consult a healthcare professional before use. - Store at ambient temperature: keep in the original packaging, protect from moisture and direct sunlight.

Paracetamol Da can interact with several medicines; awareness of the interaction level helps manage risk.

Major Interactions (Avoid): - Alcohol: concurrent use markedly increases risk of liver injury. - Warfarin: may enhance anticoagulant effect, increasing bleeding risk. - Carbamazepine: induces metabolism, reducing paracetamol efficacy. - Phenytoin: similar enzyme induction leading to lower plasma levels. - Isoniazid: can potentiate hepatotoxicity.

Moderate Interactions (Monitor Closely): - Oral contraceptives: may slightly reduce contraceptive effectiveness. - Antihypertensives: occasional reduction in blood pressure control. - Antiretrovirals (e.g., ritonavir): may alter paracetamol clearance. - High‑dose vitamin C: can increase renal excretion of paracetamol metabolites.