Europe — EMA
Paracetamol/Codeine Accord (Paracetamol, Codeine Phosphate Hemihydrate)
GNH USA supplies t
International sale not permitted. Listed for the domestic market and B2B only.
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What is Paracetamol, Codeine Phosphate Hemihydrate?
Paracetamol, the active ingredient in Paracetamol/Codeine Accord, is a combination analgesic presented as a tablet for oral use. It treats mild to moderate pain and reduces fever in adults.
GNH USA supplies Paracetamol/Codeine Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.
What is Paracetamol, Codeine Phosphate Hemihydrate used for?
Paracetamol/Codeine Accord is used for pain relief in several common clinical situations: - Dental pain: Provides effective relief of post‑extraction or procedural discomfort. - Musculoskeletal pain: Reduces pain associated with strains, sprains and low‑back injuries. - Headache and migraine relief: Alleviates moderate headache symptoms when simpler analgesics are insufficient.
What are the side effects of Paracetamol, Codeine Phosphate Hemihydrate?
Paracetamol/Codeine Accord may cause a range of adverse reactions.
Common Side Effects: - Nausea: Mild to moderate stomach upset. - Constipation: Reduced bowel movements. - Drowsiness: Feeling of sleepiness or reduced alertness. - Dizziness: Light‑headed sensation. - Dry mouth: Reduced salivation. - Sweating: Increased perspiration.
Serious or Rare Side Effects: - Respiratory depression: Slowed breathing, especially at higher doses. - Allergic reactions: Rash, itching, swelling or anaphylaxis. - Hepatotoxicity: Liver injury from excessive paracetamol exposure. - Dependence or misuse potential: Risk of opioid‑related dependence. - Severe hypotension: Marked drop in blood pressure. - Seizures: Rare occurrence, particularly with overdose.
What precautions apply to Paracetamol, Codeine Phosphate Hemihydrate?
When using Paracetamol/Codeine Accord, consider the following safety measures: - Assess liver function: Check baseline hepatic health before initiating therapy. - Limit alcohol intake: Reduce consumption to lower risk of liver injury. - Monitor for sedation: Advise patients not to operate machinery. - Evaluate renal risk: Use caution in patients with impaired kidney function. - Review concomitant CNS depressants: Adjust therapy if other sedatives are used. - Store at ambient temperature: Keep tablets in the original container, protected from moisture and direct sunlight.
What does Paracetamol, Codeine Phosphate Hemihydrate interact with?
Paracetamol/Codeine Accord can interact with several medicines. Review strong
Major Interactions (Avoid): - CYP 3‑4 t e t t t. - g ewline - ewline - -
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