GNH USA

Europe — EMA

Paracetamol/Codeine Accord (Paracetamol, Codeine Phosphate Hemihydrate)

GNH USA supplies Paracetamol/Codeine Accord (Paracetamol/Codeine), a analgesic combination for dental, musculoskeletal and headache pain.

Paracetamol, Codeine Phosphate Hemihydrate

Request sourcing

1
Pack/s

What is Paracetamol, Codeine Phosphate Hemihydrate?

Paracetamol, the active ingredient in Paracetamol/Codeine Accord, is an analgesic presented as a combination tablet for oral use. It treats mild to moderate pain and reduces fever in adults. Codeine, the second active ingredient, is an opioid analgesic that enhances pain relief when combined with paracetamol.

GNH USA supplies Paracetamol/Codeine Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Paracetamol, Codeine Phosphate Hemihydrate used for?

Paracetamol/Codeine Accord is used for pain relief in several clinical contexts: - Dental pain: Provides effective relief of postoperative dental discomfort. - Musculoskeletal pain: Reduces pain associated with strains, sprains and minor injuries. - Headache and migraine: Alleviates moderate headache symptoms when other treatments are insufficient.

What are the side effects of Paracetamol, Codeine Phosphate Hemihydrate?

Paracetamol/Codeine Accord may cause a range of adverse reactions.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Constipation: reduced bowel movements. - Drowsiness: feeling of sleepiness or reduced alertness. - Dizziness: light‑headed sensation. - Dry mouth: reduced salivation.

Serious or Rare Side Effects: - Respiratory depression: slowed breathing, especially at higher doses. - Hepatotoxicity: liver injury from excessive paracetamol exposure. - Allergic reactions: rash, itching, swelling or anaphylaxis. - Dependence or misuse: potential for opioid‑related dependence. - Severe hypotension: marked drop in blood pressure.

What precautions apply to Paracetamol, Codeine Phosphate Hemihydrate?

Paracetamol/Codeine Accord should be used with caution in specific situations: - Liver disease: avoid exceeding recommended paracetamol limits. - Renal impairment: monitor kidney function regularly. - Respiratory conditions: use carefully in patients with asthma or COPD. - Concomitant CNS depressants: may increase sedation and respiratory risk. - Pregnancy and lactation: limit use to situations where benefits outweigh risks. - Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

What does Paracetamol, Codeine Phosphate Hemihydrate interact with?

Paracetamol/Codeine Accord can interact with several medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid): - MAO inhibitors: risk of severe hypertension or serotonin syndrome. - Benzodiazepines: additive central nervous system depression. - Strong CYP2D6 inhibitors (e.g., fluoxetine, paroxetine): reduce conversion of codeine to morphine, lowering analgesic effect.

Moderate Interactions (Monitor Closely): - Alcohol: increases risk of liver toxicity and sedation. - Anticoagulants (e.g., warfarin): may enhance bleeding risk. - Antihistamines: can potentiate drowsiness. - Diuretics: may affect renal clearance of paracetamol.

Frequently asked questions

What is Paracetamol/Codeine Accord used for?+
Paracetamol/Codeine Accord is an oral analgesic combination indicated for the short‑term relief of mild to moderate pain such as dental pain, musculoskeletal aches, and tension‑type headaches when other non‑opioid options are insufficient.
How does Paracetamol/Codeine work?+
Paracetamol reduces pain by inhibiting central cyclooxygenase enzymes, while codeine is metabolised to morphine, which activates µ‑opioid receptors in the brain and spinal cord. Together they provide additive analgesia without significant anti‑inflammatory action.
What is the usual dose of Paracetamol/Codeine Accord?+
The prescribed dose is determined by the treating clinician based on the patient’s age, weight, pain severity and medical history. Healthcare professionals adjust the amount and frequency to stay within safe limits for both paracetamol and codeine.
Is Paracetamol/Codeine Accord safe during pregnancy or breastfeeding?+
Use during pregnancy or lactation is permitted only when the expected benefit outweighs potential risk. Codeine crosses the placenta and appears in breast milk, so clinicians usually limit exposure and monitor the infant for sedation or respiratory effects.
How do I order Paracetamol/Codeine Accord from GNH USA?+
Submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.
How does Paracetamol/Codeine Accord compare with other pain relievers?+
Compared with paracetamol alone, the addition of codeine offers stronger analgesia for moderate pain but introduces opioid‑related risks such as dependence and respiratory depression. It is less potent than stronger opioids like morphine, making it suitable for short‑term use.
What are the storage and handling requirements for Paracetamol/Codeine Accord?+
Store the tablets below 25 °C in their original container, protecting them from moisture, heat and direct sunlight. Keep out of reach of children and dispose of any damaged or expired product according to local regulations.
How is Paracetamol/Codeine Accord administered?+
The medication is taken orally, usually with a glass of water. It may be taken with or without food, but taking it with food can reduce stomach upset. Patients should follow the prescribing clinician’s instructions regarding timing and frequency.
What are the most serious risks associated with Paracetamol/Codeine Accord?+
Serious risks include respiratory depression, especially in opioid‑naïve individuals or when combined with other depressants, and liver injury from excessive paracetamol intake. Allergic reactions and opioid dependence are also important safety concerns.
Who should not use Paracetamol/Codeine Accord?+
Individuals with known hypersensitivity to paracetamol, codeine or any excipients, those with severe respiratory disorders, uncontrolled asthma, or significant liver impairment should avoid this product. It is also contraindicated in patients taking MAO inhibitors.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
Send a sourcing enquiry for this product →

Product details

Drug
Paracetamol, Codeine Phosphate Hemihydrate
Route
Oral Use
Manufacturer
Accord Healthcare France Sas
Origin
EU

Related products

Algocalm

Algocalm

Paracetamol, Codeine Phosphate Hemihydrate

Zentiva, K.S.
EU
Altermol

Altermol

Paracetamol, Codeine Phosphate Hemihydrate

Alternova A/S
EU
Altermol

Altermol

Paracetamol, Codeine Phosphate Hemihydrate

Alternova A/S
EU
Analgiplus

Analgiplus

Paracetamol, Codeine Phosphate Hemihydrate

Faes Farma, S.A.
EU