Europe — EMA
Paracetamol/Codeine Accord (Paracetamol, Codeine)
Paracetamol, the active ingredient in Paracetamol/Codeine Accord, is a combination analgesic presented as a strength/form for oral use. It treats mild to moderate pain and reduces fever in adult patients.
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What is Paracetamol, Codeine?
Paracetamol, the active ingredient in Paracetamol/Codeine Accord, is a combination analgesic presented as a strength/form for oral use. It treats mild to moderate pain and reduces fever in adult patients. GNH USA supplies Paracetamol/Codeine Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.
GNH USA supplies Paracetamol/Codeine Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.
What is Paracetamol, Codeine used for?
Paracetamol/Codeine Accord is a combination analgesic that acts on pain pathways and fever mechanisms. - Dental pain: Provides relief of moderate dental discomfort and inflammation. - Musculoskeletal pain: Reduces pain associated with strains, sprains and low‑back pain. - Post‑operative pain: Helps manage pain following minor surgical procedures. - Fever: Lowers elevated body temperature in adults. - Headache: Alleviates tension‑type and mild migraine headaches.
What are the side effects of Paracetamol, Codeine?
Paracetamol/Codeine Accord may cause a range of adverse reactions.
Common Side Effects: - Nausea: Mild to moderate stomach upset. - Drowsiness: Feeling of sleepiness or reduced alertness. - Constipation: Difficulty passing stools. - Dizziness: Light‑headed sensation. - Dry mouth: Reduced salivation. - Sweating: Increased perspiration.
Serious or Rare Side Effects: - Respiratory depression: Slow or shallow breathing, especially at higher doses. - Allergic reaction: Rash, itching, swelling, or anaphylaxis. - Liver toxicity: Elevated liver enzymes or hepatic injury with excessive paracetamol. - Dependence: Potential for opioid dependence with prolonged use. - Seizures: Rare occurrence, particularly in overdose. - Severe hypotension: Marked drop in blood pressure.
What precautions apply to Paracetamol, Codeine?
Paracetamol/Codeine Accord should be used with caution in specific situations. - Liver disease: Avoid or adjust dose in patients with hepatic impairment. - Renal impairment: Use cautiously in reduced kidney function. - Respiratory conditions: Monitor for respiratory depression in asthma or COPD. - Alcohol use: Limit intake as alcohol can increase liver toxicity risk. - Pregnancy and breastfeeding: Use only if clearly indicated. - Store below 25°C: Keep in the original packaging, protect from moisture and direct light.
What does Paracetamol, Codeine interact with?
Paracetamol/Codeine Accord can interact with several medicines, requiring careful management.
Major Interactions (Avoid): - MAO inhibitors: Potentially severe cardiovascular - ").
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