GNH USA

Europe — EMA

Paracetamol Centrofarm

GNH USA supplies Paracetamol Centrofarm (Paracetamol), a analgesic/antipyretic for fever and mild to moderate pain. Request a quote for global supply today.

Paracetamol

Request sourcing

1
Pack/s

What is Paracetamol?

Paracetamol, the active ingredient in Paracetamol Centrofarm, is an analgesic/antipyretic presented as a 500 mg tablet for oral use. It relieves mild to moderate pain and reduces fever in adults and children.

GNH USA supplies Paracetamol Centrofarm as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Paracetamol used for?

Paracetamol acts centrally to alleviate pain and lower elevated body temperature.

Fever: reduces high temperature associated with infection or inflammation. Headache: alleviates tension‑type or mild migraine pain. Musculoskeletal pain: provides relief from aches and strains. Dental pain: eases discomfort following dental procedures.

What are the side effects of Paracetamol?

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea or stomach discomfort. - Mild skin rash or itching. - Elevated liver enzymes in routine tests. - Headache or dizziness. - Rare taste disturbances.

Serious or Rare Side Effects: - Acute liver failure, especially with overdose or chronic high dosing. - Severe skin reactions such as Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Blood disorders including thrombocytopenia or neutropenia. - Hypersensitivity anaphylaxis. - Renal impairment in susceptible individuals.

What precautions apply to Paracetamol?

Safe use of Paracetamol requires attention to liver health, dosing limits, and co‑administered substances.

Assess liver function: avoid use in patients with severe hepatic impairment. Avoid alcohol: concurrent intake increases risk of liver injury. Use lowest effective dose: limit total daily intake to 4 g for adults. Pregnancy: consult a healthcare professional before use. Children dosing: follow pediatric guidelines and weight‑based dosing. Store at ambient temperature: keep in original container, protect from moisture.

What does Paracetamol interact with?

Paracetamol may interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Alcohol: synergistic hepatotoxic risk. - Other hepatotoxic drugs (e.g., isoniazid, valproate): increase liver injury potential. - Warfarin: may enhance anticoagulant effect, requiring INR monitoring. - Carbamazepine: may reduce analgesic efficacy.

Moderate Interactions (Monitor Closely): - Phenobarbital: induces metabolism, lowering plasma levels. - Rifampicin: increases clearance, possibly reducing effect. - Oral contraceptives: may experience reduced hormonal efficacy. - High‑dose vitamin C: can affect renal excretion of paracetamol metabolites.

Frequently asked questions

What is Paracetamol Centrofarm used for?+
Paracetamol Centrofarm is used to relieve mild to moderate pain such as headaches, musculoskeletal aches, and dental discomfort, and to lower elevated body temperature caused by fever. It is an over‑the‑counter analgesic and antipyretic suitable for adults and children when dosed according to professional guidance.
How does paracetamol work?+
Paracetamol works by inhibiting central cyclooxygenase enzymes (COX‑1 and COX‑2), which reduces the production of prostaglandins that mediate pain and fever. This central action provides analgesic and antipyretic effects while having minimal anti‑inflammatory activity in peripheral tissues.
What is the usual dose of Paracetamol Centrofarm?+
The appropriate dose of Paracetamol Centrofarm is determined by the prescribing healthcare professional based on the patient’s age, weight, and clinical condition. Adults typically receive up to 500 mg–1 g per dose, not exceeding 4 g per day, while pediatric dosing follows weight‑based recommendations.
Is Paracetamol Centrofarm safe during pregnancy or breastfeeding?+
Paracetamol is generally considered compatible with pregnancy and breastfeeding when used at the lowest effective dose for the shortest duration. However, pregnant or lactating individuals should consult their healthcare provider before starting therapy to confirm safety and appropriate dosing.
How do I order Paracetamol Centrofarm from GNH USA?+
To order Paracetamol Centrofarm, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.
How does Paracetamol Centrofarm compare with other analgesics?+
Paracetamol Centrofarm offers analgesic and antipyretic effects with a lower risk of gastrointestinal irritation compared with non‑steroidal anti‑inflammatory drugs (NSAIDs). Unlike NSAIDs, it has minimal anti‑inflammatory activity and a lower potential for platelet inhibition, making it suitable for patients who need pain relief without the bleeding risk associated with NSAIDs.
What are the storage and handling requirements for Paracetamol Centrofarm?+
Paracetamol Centrofarm should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing in humid or excessively hot environments.
How is Paracetamol Centrofarm administered?+
Paracetamol Centrofarm is administered orally. The tablet should be swallowed whole with water and can be taken with or without food. Patients should follow the dosage instructions provided by their healthcare professional and avoid crushing or chewing the tablet unless specifically advised.
What are the most serious risks associated with Paracetamol Centrofarm?+
The most serious risks include acute liver injury or failure, especially with overdose or chronic high‑dose use, and rare severe skin reactions such as Stevens‑Johnson syndrome. Patients should monitor for signs of liver dysfunction, such as jaundice or dark urine, and seek immediate medical attention if severe skin rash or allergic symptoms develop.
Who should not use Paracetamol Centrofarm?+
Paracetamol Centrofarm should be avoided by individuals with known hypersensitivity to paracetamol or any excipients in the tablet, patients with severe hepatic impairment, and those who regularly consume excessive alcohol. It should also be used with caution in patients taking other hepatotoxic medications, and pediatric use must follow weight‑based dosing guidelines.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
Send a sourcing enquiry for this product →

Product details

Drug
Paracetamol
Route
Oral Use
Manufacturer
Sc Sintofarm Sa
Origin
EU

Related products

Abalon

Abalon

Paracetamol

Tad Pharma Gmbh
EU
Acetamol

Acetamol

Paracetamol

Abiogen Pharma S.P.A.
EU
Acetamol

Acetamol

Paracetamol

Abiogen Pharma S.P.A.
EU
Acetamol Adulti

Acetamol Adulti

Paracetamol

Abiogen Pharma S.P.A.
EU