Paracetamol/Coffeïne Sam (Paracetamol, Caffeine)

Paracetamol, the active ingredient in Paracetamol/Coffeïne Sam, is an analgesic and antipyretic presented as a combination tablet for oral use. It relieves mild to moderate pain and reduces fever in adults and children. GNH USA supplies Paracetamol/Coffeïne Sam as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

GNH USA supplies Paracetamol/Coffeïne Sam as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Paracetamol/Caffeine is used for pain and fever management by acting on central pain pathways and thermoregulatory centers.

- Headache: provides relief from tension‑type and mild migraine headaches. - Fever: lowers elevated body temperature in acute febrile illnesses. - Minor musculoskeletal pain: eases discomfort from strains, sprains and backache. - Dental pain: reduces pain associated with toothache or dental procedures. - Cold‑related discomfort: alleviates sinus pressure and headache associated with common colds.

Paracetamol/Caffeine may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nausea: occasional upset stomach or feeling of queasiness. - Insomnia: difficulty falling or staying asleep, especially if taken later in the day. - Restlessness: mild agitation or feeling of being overly energetic. - Headache: paradoxical headache despite analgesic intent. - Gastrointestinal discomfort: mild abdominal pain or dyspepsia.

Serious or Rare Side Effects: - Allergic reaction: rash, itching, swelling, or difficulty breathing. - Hepatotoxicity: liver injury, particularly with excessive dosing or pre‑existing liver disease. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Anaphylaxis: rapid onset of life‑threatening allergic response. - Blood disorders: unexplained bruising, bleeding or low white‑cell counts.

When using Paracetamol/Caffeine, consider the following safety measures:

- Dose limitation: do not exceed the maximum daily amount of paracetamol to avoid liver toxicity. - Alcohol use: limit alcohol consumption as it may increase hepatic risk. - Pre‑existing liver disease: use only under medical supervision. - Pregnancy and lactation: consult a healthcare professional before use. - Drug interactions: review concomitant medications for potential additive effects. - Store at ambient temperature: keep below 25°C in the original packaging, protected from moisture.

Paracetamol/Caffeine can interact with several medicines, requiring careful management.

Major Interactions (Avoid): - Warfarin: increased risk of bleeding due to enhanced anticoagulant effect. - Highly  

Moderate