Europe — EMA
Paracetamol Brillpharma
GNH USA supplies Paracetamol Brillpharma (Paracetamol), an analgesic, antipyretic for pain and fever.
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What is Paracetamol?
Paracetamol, the active ingredient in Paracetamol Brillpharma, is an analgesic, antipyretic presented as an oral dosage form for oral use. It treats pain and fever in adults and children, providing rapid relief of mild to moderate discomfort.
GNH USA supplies Paracetamol Brillpharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol used for?
Paracetamol is an analgesic and antipyretic that reduces pain and fever by acting on the prostaglandin pathway.
- Pain: provides relief of mild to moderate pain such as headache, toothache, or muscular aches. - Fever: lowers elevated body temperature in febrile conditions. - Headache: alleviates tension‑type and mild migraine headaches. - Toothache: eases dental pain after procedures or infection. - Muscular aches: helps reduce soreness associated with strain or over‑exertion.
What are the side effects of Paracetamol?
Paracetamol is generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: mild stomach upset or feeling of queasiness. - Abdominal discomfort: occasional stomach pain or indigestion. - Rash: skin redness or mild itching. - Elevated liver enzymes: transient increase detectable in blood tests. - Headache: occasional mild headache. - Dizziness: brief sensation of light‑headedness.
Serious or Rare Side Effects: - Stevens‑Johnson syndrome: severe skin reaction requiring immediate medical attention. - Hepatic failure: rare but serious liver injury, especially with overdose. - Blood disorders: such as thrombocytopenia or agranulocytosis. - Anaphylaxis: rare allergic reaction with breathing difficulty. - Severe skin reactions: including toxic epidermal necrolysis. - Persistent vomiting: may indicate toxicity.
What precautions apply to Paracetamol?
Paracetamol should be used with awareness of potential risks and proper handling.
- Do not exceed the recommended daily dose: follow prescriber or label instructions. - Avoid use in severe liver disease: consult a healthcare professional first. - Use caution with alcohol consumption: chronic intake may increase liver toxicity. - Do not combine with other paracetamol‑containing products: risk of overdose. - Consult a physician before use in children: dosing differs by age and weight. - Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.
What does Paracetamol interact with?
Paracetamol can interact with several medicines, requiring attention to avoid adverse outcomes.
Major Interactions (Avoid): - Other paracetamol‑containing products: risk of cumulative overdose. - High‑dose alcohol: potentiates liver toxicity. - Severe liver impairment: may exacerbate hepatic injury.
Moderate Interactions (Monitor Closely): - Warfarin: may increase anticoagulant effect and bleeding risk. - Carbamazepine: can enhance hepatic metabolism, reducing efficacy. - Isoniazid: may increase risk of liver injury. - Phenytoin: may alter paracetamol clearance. - Oral contraceptives: may slightly increase plasma levels of paracetamol.



