Europe — EMA
Paracetamol Bc
GNH USA supplies Paracetamol Bc (Paracetamol), a analgesic and antipyretic for pain and fever relief. Request a quote for global supply and distribution.
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What is Paracetamol?
Paracetamol, the active ingredient in Paracetamol Bc, is an analgesic and antipyretic presented as an unspecified strength oral tablet for oral use. It is used to relieve mild to moderate pain and to lower fever in adults and children, and is available over‑the‑counter in the EU market.
GNH USA supplies Paracetamol Bc as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance.
What is Paracetamol used for?
Paracetamol works as a centrally acting analgesic and antipyretic, reducing pain and fever across several common conditions.
Pain: provides relief of mild to moderate nociceptive pain. Fever: lowers elevated body temperature. Headache: alleviates tension‑type and mild migraine headaches. Musculoskeletal pain: eases discomfort from muscle strains and joint aches.
What are the side effects of Paracetamol?
Paracetamol is generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea or mild stomach upset. - Transient dizziness or light‑headedness. - Skin rash or mild itching. - Elevated liver enzymes in routine tests. - Headache (when used for other indications). - Fatigue or drowsiness.
Serious or Rare Side Effects: - Severe hepatotoxicity, especially with overdose. - Allergic reactions such as angioedema or anaphylaxis. - Blood dyscrasias including thrombocytopenia. - Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Acute renal failure in susceptible individuals. - Severe skin reactions like drug reaction with eosinophilia and systemic symptoms (DRESS).
What precautions apply to Paracetamol?
Paracetamol should be used with caution and according to recommended guidelines.
Do not exceed total daily dose: adhere to the maximum 4 g per 24 hours for adults. Use with caution in liver disease: assess hepatic function before chronic use. Avoid concurrent alcohol: combined use increases risk of liver injury. Use with caution in renal impairment: monitor kidney function when dosing is prolonged. Not recommended for children under the specified age without medical advice. Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.
What does Paracetamol interact with?
Paracetamol can interact with several medicines, affecting efficacy or safety.
Major Interactions (Avoid): - Alcohol: synergistic hepatotoxic risk. - Warfarin: may enhance anticoagulant effect and increase INR. - Carbamazepine: induces metabolism, reducing paracetamol levels. - Rifampicin: increases hepatic clearance, lowering efficacy. - Other hepatotoxic drugs (e.g., isoniazid): combined use raises liver injury risk.
Moderate Interactions (Monitor Closely): - Anticonvulsants such as phenytoin: may alter plasma concentrations. - HIV protease inhibitors: can affect metabolic pathways. - Oral contraceptives: may experience reduced effectiveness. - Certain antidepressants (e.g., SSRIs): monitor for additive side effects.



