GNH USA

Europe — EMA

Paracetamol Baxter

GNH USA supplies Paracetamol Baxter (Paracetamol), an analgesic for pain and fever. Request a quote for global supply of this GMP‑certified product today.

Paracetamol

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What is Paracetamol?

Paracetamol, the active ingredient in Paracetamol Baxter, is an analgesic presented as a solution for injection for intravenous use. It is indicated for short‑term management of mild to moderate pain and febrile conditions in both adult and pediatric populations when oral administration is not feasible.

GNH USA supplies Paracetamol Baxter as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality, regulatory adherence, and reliable logistics for global healthcare providers. Our compliance with Good Distribution Practice and robust quality assurance systems supports consistent product performance across diverse markets.

What is Paracetamol used for?

Paracetamol is used to manage pain and fever by acting on the central nervous system.

Pain: provides analgesic relief for mild to moderate pain Fever: reduces elevated body temperature Postoperative discomfort: alleviates pain after surgical procedures Headache: relieves tension‑type headache Musculoskeletal pain: eases mild musculoskeletal discomfort

What are the side effects of Paracetamol?

Paracetamol administered intravenously may be associated with a range of adverse reactions.

Common Side Effects: - Injection site pain: mild discomfort at the infusion site - Nausea: transient feeling of queasiness - Transient hypotension: brief drop in blood pressure - Flushing: temporary skin redness - Dizziness: mild vertigo

Serious or Rare Side Effects: - Anaphylaxis: severe allergic reaction with airway compromise - Severe hypotension: marked drop in blood pressure requiring intervention - Stevens‑Johnson syndrome: rare severe skin reaction - Hepatic toxicity: potential liver injury, especially with overdose - Thrombophlebitis: inflammation of vein with clot formation - Severe skin reactions: such as toxic epidermal necrolysis

What precautions apply to Paracetamol?

When using Paracetamol Baxter, consider the following precautions to ensure safe administration.

- Assess liver function: evaluate hepatic status before and during therapy - Use with caution in hepatic impairment: adjust dosing or avoid as clinically indicated - Avoid in known hypersensitivity: do not administer to patients with prior allergic reaction to paracetamol - Monitor for signs of anaphylaxis: observe patient during and after infusion - Adjust dose in renal impairment: consider reduced dosing in severe kidney dysfunction - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake

What does Paracetamol interact with?

Paracetamol may interact with other medications, influencing efficacy or safety.

Major Interactions (Avoid): - Concurrent paracetamol-containing products: risk of overdose and hepatotoxicity - Hepatotoxic drugs (e.g., isoniazid, valproate): increased risk of liver injury - Warfarin: may enhance anticoagulant effect and bleeding risk

Moderate Interactions (Monitor Closely): - Alcohol consumption: additive liver stress, monitor hepatic function - CYP450 enzyme inducers (e.g., carbamazepine, phenytoin): may reduce paracetamol effectiveness - Certain anticonvulsants (e.g., phenobarbital): may alter metabolism and require monitoring

Frequently asked questions

What is Paracetamol Baxter used for?+
Paracetamol Baxter is an intravenous formulation of paracetamol indicated for the short‑term relief of mild to moderate pain and for the reduction of fever in adult and pediatric patients when oral administration is not suitable.
How does paracetamol work?+
Paracetamol works by inhibiting cyclooxygenase enzymes in the central nervous system, which reduces the synthesis of prostaglandins. Lower prostaglandin levels diminish pain signal transmission and reset the hypothalamic set‑point for body temperature, producing analgesic and antipyretic effects.
What determines the dose of Paracetamol Baxter?+
The dose of Paracetamol Baxter is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and overall health status. No fixed dosing regimen is provided here; the prescriber sets the appropriate amount.
Is Paracetamol Baxter safe in pregnancy or breastfeeding?+
Safety data for intravenous paracetamol during pregnancy and lactation are limited. It should only be used if the potential benefit outweighs any possible risk, and the decision must be made by a qualified healthcare professional.
How do I order Paracetamol Baxter from GNH USA?+
To order Paracetamol Baxter, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.
How does Paracetamol Baxter compare with other IV analgesics?+
Paracetamol Baxter offers analgesic and antipyretic effects without the opioid‑related respiratory depression seen with many IV analgesics. Compared with non‑steroidal anti‑inflammatory drugs, it has minimal anti‑inflammatory activity and a lower risk of gastrointestinal irritation, but similar caution regarding hepatic function applies.
How should Paracetamol Baxter be stored and handled?+
Paracetamol Baxter must be stored at 2‑8 °C in a refrigerator, protected from light. Do not freeze or shake the solution. Before use, inspect the vial for particulate matter and ensure the container remains sealed until administration.
How is Paracetamol Baxter administered?+
Paracetamol Baxter is administered intravenously by a qualified healthcare professional. The solution is typically diluted in a compatible IV fluid and infused over a short period, following the dosing instructions provided by the prescriber and institutional protocols.
What are the most serious risks associated with Paracetamol Baxter?+
The most serious risks include severe allergic reactions such as anaphylaxis, marked hypotension, rare but severe skin reactions like Stevens‑Johnson syndrome or toxic epidermal necrolysis, and potential hepatic toxicity, especially when combined with other hepatotoxic agents or overdosed.
Who should not use Paracetamol Baxter?+
Paracetamol Baxter should be avoided in patients with known hypersensitivity to paracetamol or any component of the formulation, in individuals with severe hepatic impairment unless specifically directed by a physician, and in patients for whom an alternative therapy is more appropriate based on clinical judgment.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Paracetamol
Route
Intravenous Use
Manufacturer
Baxter Holding B.V.
Origin
EU

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