GNH USA

Europe — EMA

Paracetamol Basi

GNH USA supplies Paracetamol Basi (Paracetamol), an analgesic/antipyretic for fever and mild‑to‑moderate pain.

Paracetamol

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What is Paracetamol?

Paracetamol, the active ingredient in Paracetamol Basi, is an analgesic presented as an unspecified strength oral tablet for systemic use. It is used to relieve mild to moderate pain and reduce fever in adults and children. GNH USA supplies Paracetamol Basi as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Paracetamol used for?

Paracetamol acts on the prostaglandin pathway to alleviate pain and lower temperature. - Fever: reduces elevated body temperature in acute febrile states. - Mild to moderate pain: eases headache, toothache, musculoskeletal discomfort and dysmenorrhoea. - Cold/flu symptoms: helps relieve discomfort associated with common cold and influenza.

What are the side effects of Paracetamol?

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea: mild stomach upset after ingestion. - Abdominal discomfort: transient pain or fullness. - Rash or mild skin irritation. - Elevated liver enzymes: usually reversible. - Headache: occasional occurrence. - Dizziness: transient light‑headedness.

Serious or Rare Side Effects: - Severe liver injury or hepatic failure, especially with overdose. - Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Blood dyscrasias such as agranulocytosis or thrombocytopenia. - Anaphylactic reactions: rare but potentially life‑threatening. - Renal impairment in prolonged high‑dose use. - Hypersensitivity reactions: including angioedema.

What precautions apply to Paracetamol?

Paracetamol should be used with caution in specific clinical situations. - Hepatic impairment: adjust dose or avoid use in severe liver disease. - Alcohol consumption: limit intake to reduce risk of liver toxicity. - Maximum daily dose: do not exceed the recommended total amount from all sources. - Renal impairment: monitor renal function in patients with chronic kidney disease. - Pregnancy and breastfeeding: consult a healthcare professional before use. - Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

What does Paracetamol interact with?

Paracetamol may interact with several medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid): - Concurrent use with other paracetamol‑containing products: risk of overdose. - Strong CYP450 inducers (e.g., rifampicin, carbamazepine): may lower plasma levels. - High‑dose alcohol: potentiates hepatotoxicity.

Moderate Interactions (Monitor Closely): - Warfarin: may increase INR and bleeding risk. - Isoniazid: can enhance hepatotoxic potential. - Antiepileptic drugs (e.g., phenytoin): may alter metabolism. - Certain antiviral agents: may affect liver enzyme activity.

Frequently asked questions

What is Paracetamol Basi used for?+
Paracetamol Basi is a generic formulation of paracetamol, employed to relieve mild to moderate pain such as headache, toothache, and musculoskeletal discomfort, and to reduce fever associated with infections or inflammatory conditions. It is commonly used in both adult and pediatric populations under medical guidance.
How does paracetamol work in the body?+
Paracetamol works by inhibiting cyclooxygenase enzymes, mainly COX‑2, within the central nervous system. This reduces the production of prostaglandins, which are chemical messengers that trigger pain sensations and raise body temperature, thereby providing analgesic and antipyretic effects without significant peripheral anti‑inflammatory activity.
What is the usual dose of Paracetamol Basi?+
The appropriate dose of Paracetamol Basi is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and overall health status. It is essential to follow the prescriber’s instructions and not exceed the recommended total daily amount from all sources.
Is Paracetamol Basi safe during pregnancy or breastfeeding?+
Paracetamol is generally considered the analgesic/antipyretic of choice during pregnancy and lactation when used at recommended doses. However, pregnant or breastfeeding individuals should consult their healthcare provider before starting treatment to ensure safety for both mother and child.
How do I order Paracetamol Basi from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.
How does Paracetamol Basi compare with other analgesics?+
Paracetamol differs from non‑steroidal anti‑inflammatory drugs (NSAIDs) by lacking significant peripheral anti‑inflammatory activity and having a lower risk of gastrointestinal irritation. It is often preferred when NSAIDs are contraindicated, but it does not provide the anti‑inflammatory benefits that NSAIDs offer.
What are the storage and handling requirements for Paracetamol Basi?+
Paracetamol Basi should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in humid or excessively hot environments.
How is Paracetamol Basi administered?+
Paracetamol Basi is administered orally, typically as a tablet that is swallowed with water. The exact route and method of administration should follow the prescribing information provided by the healthcare professional.
What are the most serious risks associated with Paracetamol Basi?+
The most serious risks include severe liver injury or hepatic failure, especially when the maximum daily dose is exceeded or combined with alcohol. Rare but severe skin reactions such as Stevens‑Johnson syndrome and blood disorders like agranulocytosis may also occur.
Who should not use Paracetamol Basi?+
Individuals with known hypersensitivity to paracetamol, severe hepatic impairment, or those who have already exceeded the recommended daily dose of paracetamol from other sources should avoid using Paracetamol Basi. Pregnant or breastfeeding patients should seek medical advice before use.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Paracetamol
Route
Intravenous Use
Manufacturer
Laboratórios Basi – Indústria Farmacêutica, S.A.
Origin
EU

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