GNH USA

Europe — EMA

Paracetamol B. Braun

GNH USA supplies Paracetamol B. Braun (Paracetamol), a analgesic, antipyretic for pain and fever, available as an intravenous solution for hospital use.

Paracetamol

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What is Paracetamol?

Paracetamol, the active ingredient in Paracetamol B. Braun, is an analgesic and antipyretic presented as an intravenous solution for intravenous use. It provides rapid reduction of pain and fever in adult and pediatric patients when oral administration is not feasible.

GNH USA supplies Paracetamol B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide, delivering EU‑quality products through regulated supply chains.

What is Paracetamol used for?

Paracetamol is used to manage pain and fever by acting on the central nervous system.

- Pain: provides rapid analgesic relief in acute and postoperative settings. - Fever: lowers elevated body temperature by resetting the hypothalamic set‑point. - Post‑operative pain: alleviates discomfort after surgical procedures. - Acute migraine: helps reduce headache intensity. - Dental pain: diminishes pain associated with dental interventions.

What are the side effects of Paracetamol?

Paracetamol may be associated with a range of adverse reactions, varying from mild to severe.

Common Side Effects: - Nausea: occasional gastrointestinal upset. - Injection site pain: discomfort at the infusion site. - Rash: mild skin eruption. - Elevated liver enzymes: transient increase in hepatic markers.

Serious or Rare Side Effects: - Severe hepatotoxicity: potential liver failure with overdose. - Anaphylaxis: rare severe allergic reaction. - Stevens‑Johnson syndrome: rare severe skin disorder.

What precautions apply to Paracetamol?

Paracetamol requires careful consideration in several clinical situations.

- Dose adjustment in hepatic impairment: reduce dose or avoid in severe liver disease. - Avoid in known hypersensitivity to paracetamol: discontinue use immediately. - Monitor liver function tests: especially with prolonged therapy. - Use with caution in renal impairment: adjust dosing as needed. - Concurrent use with other hepatotoxic drugs: increase risk of liver injury. - Store at ambient temperature: keep in original container, protect from light and moisture.

What does Paracetamol interact with?

Paracetamol can interact with several medications, necessitating monitoring.

Major Interactions (Avoid): - Concurrent use with other paracetamol‑containing products: risk of overdose. - Co‑administration with strong CYP450 inducers (e.g., rifampicin): may reduce efficacy. - Combination with warfarin: may increase bleeding risk.

Moderate Interactions (Monitor Closely): - Alcohol consumption: enhances hepatotoxic potential. - Use with other hepatotoxic agents (e.g., isoniazid): monitor liver function. - Concurrent NSAIDs: may increase renal risk.

Frequently asked questions

What is Paracetamol B. Braun used for?+
Paracetamol B. Braun is an intravenous formulation of paracetamol used in hospital settings to provide rapid relief of moderate to severe pain and to reduce fever when oral administration is not practical or contraindicated.
How does paracetamol work?+
Paracetamol works by inhibiting cyclooxygenase enzymes, particularly COX‑3, in the central nervous system. This reduces the synthesis of prostaglandins that mediate pain and fever, thereby providing analgesic and antipyretic effects.
What is the usual dose of Paracetamol B. Braun?+
The appropriate dose is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and liver function. Healthcare professionals set the exact regimen according to established guidelines and individual needs.
Is Paracetamol B. Braun safe in pregnancy or breastfeeding?+
Safety data for intravenous paracetamol during pregnancy and lactation are limited. Clinicians should evaluate the risk‑benefit ratio and consider alternative therapies when possible. Consultation with a specialist is recommended.
How do I order Paracetamol B. Braun from GNH USA?+
Enquiries are submitted via the product page on gnh-usa.com, where the required quantity is entered. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.
How does Paracetamol B. Braun compare with other IV analgesics?+
Compared with IV non‑steroidal anti‑inflammatory drugs (e.g., ketorolac) or opioids, IV paracetamol offers analgesia and antipyresis with a lower risk of gastrointestinal bleeding and respiratory depression. It is often used as part of multimodal pain management to reduce opioid requirements.
What are the storage and handling requirements for Paracetamol B. Braun?+
The product should be stored at ambient temperature, below 25 °C, in its original packaging. It must be protected from light, moisture and extreme temperatures. Once opened, use according to the manufacturer’s stability guidelines.
How is Paracetamol B. Braun administered?+
Paracetamol B. Braun is given by intravenous infusion. The solution is diluted in an appropriate compatible fluid and administered over the recommended time period, typically 15 minutes, under aseptic conditions by qualified healthcare personnel.
What are the most serious risks associated with Paracetamol B. Braun?+
The most serious adverse events include severe hepatotoxicity, especially with overdose, and rare hypersensitivity reactions such as anaphylaxis or Stevens‑Johnson syndrome. Prompt recognition and discontinuation are essential if these occur.
Who should not use Paracetamol B. Braun?+
Patients with known hypersensitivity to paracetamol, severe hepatic impairment, or those receiving other paracetamol‑containing products should avoid this medication. Caution is also advised in individuals with significant renal dysfunction.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Paracetamol
Route
Intravenous Use
Manufacturer
B.Braun Melsungen Ag
Origin
EU

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