GNH USA

Europe — EMA

Paracetamol B. Braun

GNH USA supplies Paracetamol B. Braun (Paracetamol), a analgesic/antipyretic for pain, fever and postoperative analgesia. Request a quote for global supply.

Paracetamol

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What is Paracetamol?

Paracetamol, the active ingredient in Paracetamol B. Braun, is an analgesic and antipyretic presented as an injectable solution for intravenous use. It is employed to relieve mild to moderate pain, reduce fever, and provide postoperative analgesia in adult and pediatric hospital patients, under medical supervision and is commonly used in surgical recovery settings.

GNH USA supplies Paracetamol B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with reliable cold‑chain logistics and regulatory support, ensuring product integrity from manufacture to end‑user.

What is Paracetamol used for?

Paracetamol B. Braun is an intravenous analgesic/antipyretic used to manage pain and fever.

Pain: rapid relief of mild to moderate acute pain, such as musculoskeletal injury, dental pain, or postoperative discomfort. Fever: effective reduction of elevated body temperature caused by infection, inflammation, or other febrile conditions. Postoperative analgesia: provides controlled analgesia after surgical procedures, helping to improve patient comfort and facilitate early mobilization. Headache: alleviates tension‑type headache and can be used for mild migraine attacks when other therapies are unsuitable.

What are the side effects of Paracetamol?

Paracetamol administered intravenously may be associated with several adverse reactions, ranging from common, mild events to rare but serious conditions.

Common Side Effects: - Injection site pain: mild discomfort at the infusion site. - Nausea: transient feeling of queasiness. - Transient hypotension: brief drop in blood pressure during rapid infusion. - Elevated liver enzymes: mild increase in transaminases without clinical symptoms.

Serious or Rare Side Effects: - Anaphylaxis: severe allergic reaction with rash, bronchospasm, or circulatory collapse. - Severe hepatotoxicity: acute liver injury, especially with overdose or pre‑existing liver disease. - Blood dyscrasias: rare cases of thrombocytopenia or leukopenia.

What precautions apply to Paracetamol?

When using Paracetamol B. Braun, clinicians should observe several safety measures to minimize risk.

Dose adjustment: modify dose in patients with hepatic impairment. Renal function: monitor renal status, especially in prolonged therapy. Concurrent hepatotoxic drugs: avoid or use with caution when combined with other liver‑affecting medications. Allergy history: assess for prior hypersensitivity to paracetamol or related compounds. Pregnancy and lactation: consider potential risks; use only if clearly indicated. Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Paracetamol interact with?

Paracetamol can interact with other medicines, affecting its metabolism or increasing toxicity.

Major Interactions (Avoid): - Warfarin: increased anticoagulant effect, monitor INR closely. - Isoniazid: heightened risk of hepatotoxicity when combined.

Moderate Interactions (Monitor Closely): - Alcohol: additive liver stress, advise limited consumption. - Other hepatotoxic agents (e.g., certain antiepileptics): monitor liver function tests. - Enzyme inducers (e.g., carbamazepine, rifampicin): may reduce paracetamol plasma levels.

Frequently asked questions

What is Paracetamol B. Braun used for?+
Paracetamol B. Braun is an intravenous formulation of paracetamol used to relieve mild to moderate pain, reduce fever, and provide postoperative analgesia in hospital settings. It is indicated for acute pain conditions, febrile states, and as part of multimodal analgesic regimens after surgery.
How does paracetamol work?+
Paracetamol works by inhibiting cyclooxygenase enzymes in the central nervous system, which lowers the production of prostaglandins that mediate pain and fever. This central inhibition reduces the perception of pain and resets the hypothalamic set‑point for body temperature, producing antipyretic effects.
What is the usual dose of Paracetamol B. Braun?+
The dose of Paracetamol B. Braun is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and hepatic function. No fixed dosing schedule is provided here; healthcare professionals should follow local guidelines and product labeling when prescribing.
Is Paracetamol B. Braun safe in pregnancy or breastfeeding?+
Safety data for intravenous paracetamol during pregnancy and lactation are limited. It should only be used when clearly needed and after evaluating the risk‑benefit ratio. Clinicians are advised to consult obstetric guidelines and consider alternative therapies if appropriate.
How do I order Paracetamol B. Braun from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com with the required quantity. GNH USA supplies hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where required) and import documentation.
How does Paracetamol B. Braun compare with other IV analgesics?+
Compared with other intravenous analgesics such as ketorolac or morphine, paracetamol offers analgesia without significant anti‑inflammatory activity or opioid‑related respiratory depression. It is often used in multimodal regimens to reduce opioid requirements, but it may be less potent for severe nociceptive pain than NSAIDs or opioids.
How should Paracetamol B. Braun be stored and handled?+
Paracetamol B. Braun must be stored at 2‑8 °C, protected from light, and must not be frozen or shaken. The solution should be kept in its original packaging until use, and any unused portion should be discarded according to local pharmacy disposal regulations.
How is Paracetamol B. Braun administered?+
The product is given by intravenous infusion. It is typically diluted in an appropriate compatible fluid and administered over a short period, often 10‑15 minutes, under aseptic conditions. Administration rate and volume should follow the prescribing information and institutional protocols.
What are the most serious risks associated with Paracetamol B. Braun?+
The most serious adverse events include severe hepatotoxicity, especially in overdose or in patients with pre‑existing liver disease, and anaphylactic reactions that can be life‑threatening. Rare blood dyscrasias such as thrombocytopenia or leukopenia have also been reported.
Who should not use Paracetamol B. Braun?+
Paracetamol B. Braun is contraindicated in individuals with known hypersensitivity to paracetamol or any component of the formulation, and in patients with severe hepatic impairment. Caution is also advised for those with active alcohol misuse, severe renal disease, or a history of drug‑induced liver injury.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Paracetamol
Route
Intravenous Use
Manufacturer
B.Braun Melsungen Ag
Origin
EU

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