GNH USA

Europe — EMA

Paracetamol B. Braun

GNH USA supplies Paracetamol B. Braun (Paracetamol), a analgesic/antipyretic for pain, fever and postoperative analgesia. Request a quote for global supply.

Paracetamol

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What is Paracetamol?

Paracetamol, the active ingredient in Paracetamol B. Braun, is an analgesic presented as an injectable solution for intravenous use. It provides relief from pain, reduces fever, and is employed for postoperative analgesia in hospital settings, particularly for adult patients requiring rapid onset of effect.

GNH USA supplies Paracetamol B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, clinics and pharmacies, through reliable logistics and regulatory support globally.

What is Paracetamol used for?

Paracetamol, an analgesic/antipyretic, is used in clinical settings to manage pain and fever.

- Pain: Provides analgesic relief for mild to moderate pain, especially postoperative or acute pain. - Fever: Reduces elevated body temperature by acting on the hypothalamic set‑point. - Postoperative analgesia: Offers rapid intravenous pain control after surgical procedures.

What are the side effects of Paracetamol?

Paracetamol may be associated with a range of adverse reactions, varying from mild to serious.

Common Side Effects: - Nausea: Mild stomach upset that may resolve without intervention. - Vomiting: Occasional emesis following administration. - Rash: Mild skin irritation or erythema. - Elevated liver enzymes: Transient increase detectable on laboratory testing.

Serious or Rare Side Effects: - Hepatotoxicity: Severe liver injury, particularly with overdose or prolonged high dosing. - Anaphylaxis: Rare, life‑threatening allergic reaction requiring immediate medical attention. - Stevens‑Johnson syndrome: Rare severe skin reaction characterized by blistering and mucosal involvement.

What precautions apply to Paracetamol?

When using intravenous paracetamol, clinicians should observe several safety precautions to minimize risk.

- Dose adjustment: Modify dose in patients with hepatic impairment. - Monitoring: Check liver function tests during prolonged therapy. - Allergies: Assess for known hypersensitivity to paracetamol or excipients. - Concomitant drugs: Avoid concurrent use with other hepatotoxic agents when possible. - Pregnancy: Use only if benefits outweigh risks, as safety data are limited. - Store at 2-8°C: Keep refrigerated, protect from light, do not freeze or shake.

What does Paracetamol interact with?

Paracetamol can interact with other medicines, influencing its efficacy or safety profile.

Major Interactions (Avoid): - Warfarin: May increase anticoagulant effect; monitor INR closely. - Isoniazid: Heightened risk of liver toxicity when combined.

Moderate Interactions (Monitor Closely): - Antiepileptics (e.g., carbamazepine): May reduce paracetamol plasma levels. - Alcohol: Additive hepatotoxic risk, especially with chronic use. - Other hepatotoxic drugs: Monitor liver function when used together.

Frequently asked questions

What is Paracetamol B. Braun used for?+
Paracetamol B. Braun is an intravenous formulation of paracetamol used to provide rapid analgesic relief for pain, reduce fever, and manage postoperative discomfort in hospital settings. It is commonly administered when a quick onset of action is required, such as after surgery or in acute care environments.
How does paracetamol work?+
Paracetamol works by inhibiting the synthesis of prostaglandins in the central nervous system, primarily through blockade of cyclooxygenase enzymes. This reduces the formation of pain‑inducing and fever‑inducing mediators, leading to decreased nociceptive signaling and a lowered hypothalamic set‑point for body temperature.
What is the usual dose of Paracetamol B. Braun?+
The appropriate dose of Paracetamol B. Braun is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and overall treatment plan. Healthcare professionals follow local guidelines and product labeling to calculate the exact amount required for each individual case.
Is Paracetamol B. Braun safe in pregnancy or breastfeeding?+
Safety data for intravenous paracetamol during pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Clinicians should evaluate each case carefully and consider alternative therapies when appropriate.
How do I order Paracetamol B. Braun from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies, and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials and respond with pricing, availability, shipping details (including cold‑chain handling if needed), and any required import documentation.
How does Paracetamol B. Braun compare with other IV analgesics?+
Compared with other intravenous analgesics such as ibuprofen or ketorolac, paracetamol offers effective pain relief and fever reduction with a lower risk of gastrointestinal irritation and platelet dysfunction. However, it lacks significant anti‑inflammatory activity, and its safety profile requires careful monitoring of liver function, especially in patients with pre‑existing hepatic disease.
What are the storage and handling requirements for Paracetamol B. Braun?+
Paracetamol B. Braun should be stored at 2‑8 °C (refrigerated), protected from light, and must not be frozen or shaken. The solution should be kept in its original container until use, and any unused portion should be discarded according to local regulations after the recommended in‑use period.
How is Paracetamol B. Braun administered?+
The product is administered intravenously by a healthcare professional. It is typically diluted in an appropriate compatible IV fluid and infused over a short period, following the dosage instructions provided by the prescriber and the product’s labeling. Administration should be performed under aseptic conditions.
What are the most serious risks associated with Paracetamol B. Braun?+
The most serious risks include hepatotoxicity, which can lead to severe liver injury, especially with overdose or in patients with existing liver disease, and rare allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome. Prompt recognition of these events and immediate medical intervention are essential.
Who should not use Paracetamol B. Braun?+
Paracetamol B. Braun should be avoided in individuals with known hypersensitivity to paracetamol or any of its excipients, and in patients with severe hepatic impairment or active liver disease. Caution is also advised for patients taking multiple hepatotoxic medications or those with a history of severe allergic reactions.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Paracetamol
Route
Intravenous Use
Manufacturer
B.Braun Melsungen Ag
Origin
EU

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