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What is Paracetamol?
Paracetamol, the active ingredient in Paracetamol B. Braun, is an analgesic presented as a strength/form for oral use. It treats mild to moderate pain and reduces fever in adults and children. GNH USA supplies Paracetamol B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
GNH USA supplies Paracetamol B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol used for?
Paracetamol B. Braun is an analgesic and antipyretic that acts on the body's pain and temperature regulation pathways.
- Fever: Reduces elevated body temperature in acute febrile states. - Headache: Alleviates mild to moderate tension‑type headaches. - Musculoskeletal pain: Relieves minor muscle and joint discomfort. - Dental pain: Provides relief from postoperative dental pain. - Osteoarthritis pain: Helps manage mild pain associated with osteoarthritis.
What are the side effects of Paracetamol?
Paracetamol is generally well‑tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: Mild stomach upset may be experienced. - Rash: Occasional skin redness or mild itching. - Elevated liver enzymes: Transient increase in liver function test values. - Headache: May persist or appear despite treatment.
Serious or Rare Side Effects: - Hepatotoxicity: Potential liver injury with excessive dosing. - Stevens‑Johnson syndrome: Severe skin reaction requiring immediate medical attention. - Anaphylaxis: Rare allergic reaction with breathing difficulty. - Blood disorders: Unusual bruising or bleeding tendencies.
What precautions apply to Paracetamol?
Paracetamol should be used with awareness of potential risks and specific patient factors.
- Dose adjustment: Reduce dose in patients with hepatic impairment. - Alcohol use: Limit intake as concurrent alcohol may increase liver toxicity. - Pregnancy: Use only under medical supervision, especially in the third trimester. - Children: Ensure appropriate pediatric formulation and dosing. - Drug interactions: Review concomitant medications for additive hepatotoxic risk. - Store below 25°C: Keep in the original packaging, protect from moisture and direct sunlight.
What does Paracetamol interact with?
Paracetamol may interact with several medicines, requiring monitoring or avoidance.
Major Interactions (Avoid): - Warfarin: Increased anticoagulant effect leading to bleeding risk. - Isoniazid: Heightened risk of liver toxicity.
Moderate Interactions (Monitor Closely): - Antiepileptic drugs (e.g., carbamazepine, phenytoin): May alter paracetamol metabolism. - Rifampicin - Fluoroquinolone antibiotics - HIV‑SARS t
