GNH USA

Europe — EMA

Paracetamol B. Braun

GNH USA supplies Paracetamol B. Braun (Paracetamol), an analgesic/antipyretic for pain and fever in hospital settings. Request a quote for worldwide supply.

Paracetamol

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What is Paracetamol?

Paracetamol, the active ingredient in Paracetamol B. Braun, is an analgesic presented as an intravenous solution for intravenous use. It provides relief of pain and reduces fever in patients requiring parenteral therapy, including postoperative and acute care settings.

GNH USA supplies Paracetamol B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution. Clients benefit from comprehensive regulatory support and consistent product availability across multiple markets.

What is Paracetamol used for?

Paracetamol acts on the cyclooxygenase pathway to provide analgesic and antipyretic effects.

Pain: provides analgesic relief in acute and chronic pain conditions. Fever: reduces elevated body temperature in febrile states. Post‑operative pain: offers rapid analgesia after surgical procedures when oral administration is not feasible. Headache: alleviates tension‑type and migraine‑associated headache pain. Musculoskeletal pain: eases discomfort from sprains, strains, and inflammatory conditions.

What are the side effects of Paracetamol?

Paracetamol administered intravenously may be associated with several adverse reactions, ranging from mild to severe.

Common Side Effects: - Nausea: mild nausea may occur during or after infusion. - Vomiting: occasional vomiting post‑administration. - Injection site discomfort: transient pain or irritation at the IV site. - Headache: mild headache reported in some patients.

Serious or Rare Side Effects: - Anaphylaxis: severe allergic reaction requiring immediate medical attention. - Stevens‑Johnson syndrome: rare severe skin reaction. - Hepatotoxicity: elevated liver enzymes or liver injury, especially with overdose. - Hypotension: sudden drop in blood pressure during infusion.

What precautions apply to Paracetamol?

When using intravenous paracetamol, several precautions should be observed to ensure patient safety. - Renal function: assess renal function and adjust use in patients with severe impairment. - Hepatic function: avoid or use with caution in patients with significant liver disease. - Allergy history: discontinue immediately if signs of hypersensitivity or rash develop. - Concomitant hepatotoxic drugs: review other medications that may increase liver risk. - Pregnancy and lactation: use only if potential benefit justifies potential risk to fetus or infant. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Paracetamol interact with?

Paracetamol can interact with other medicines; awareness of major and moderate interactions helps prevent adverse outcomes.

Major Interactions (Avoid): - Concomitant hepatotoxic agents: avoid use with other drugs that can damage the liver, such as high‑dose ibuprofen or certain antitubercular agents. - Alcohol: chronic alcohol consumption increases risk of liver injury. - Warfarin: may enhance anticoagulant effect and increase bleeding risk. - Other paracetamol‑containing products: risk of overdose when combined with additional paracetamol sources.

Moderate Interactions (Monitor Closely): - CYP450 inducers: drugs like rifampicin may reduce paracetamol plasma levels. - High‑dose aspirin: may increase risk of renal impairment when used together.

Frequently asked questions

What is Paracetamol B. Braun used for?+
Paracetamol B. Braun is an intravenous formulation of paracetamol used to relieve moderate to severe pain and to reduce fever in patients who require a parenteral route, such as those in postoperative care, intensive care, or who cannot take oral medication.
How does paracetamol work?+
Paracetamol works by inhibiting cyclooxygenase enzymes, especially COX‑2, within the central nervous system. This reduces the production of prostaglandins that signal pain and fever, providing analgesic and antipyretic effects without significant peripheral anti‑inflammatory activity.
What determines the usual dose of Paracetamol B. Braun?+
The appropriate dose of Paracetamol B. Braun is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and overall health status. Dosage regimens are individualized and should follow the prescriber’s instructions.
Is Paracetamol B. Braun safe during pregnancy or breastfeeding?+
Safety in pregnancy and lactation has not been definitively established for the intravenous formulation. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and after careful consideration by the treating physician.
How do I order Paracetamol B. Braun from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.
How does Paracetamol B. Braun compare with other analgesic options?+
Compared with non‑steroidal anti‑inflammatory drugs, intravenous paracetamol offers analgesia and antipyresis without significant platelet inhibition or gastrointestinal irritation. It is often chosen when rapid onset is needed, when oral administration is not possible, or when NSAIDs are contraindicated due to renal or bleeding risks.
How should Paracetamol B. Braun be stored and handled?+
The product should be stored at 2‑8 °C in a refrigerator, protected from light. It must not be frozen or shaken. Prior to use, inspect the solution for particulate matter or discoloration and allow it to reach room temperature if required by the administration protocol.
How is Paracetamol B. Braun administered?+
Paracetamol B. Braun is administered intravenously by a qualified healthcare professional. It is typically given as a slow infusion over several minutes, following aseptic technique and the dosing instructions provided by the prescriber.
What are the most serious risks associated with Paracetamol B. Braun?+
Serious risks include severe allergic reactions such as anaphylaxis, rare skin disorders like Stevens‑Johnson syndrome, and hepatotoxicity, especially when used in excess or with other liver‑affecting agents. Sudden hypotension during infusion is also a critical adverse event that requires immediate monitoring.
Who should not use Paracetamol B. Braun?+
Patients with known hypersensitivity to paracetamol or any component of the formulation should avoid it. It is also contraindicated in individuals with severe hepatic impairment, those receiving other paracetamol‑containing products, and patients for whom the risk of liver injury outweighs the therapeutic benefit.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Paracetamol
Route
Intravenous Use
Manufacturer
B.Braun Adria D.O.O.
Origin
EU

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