GNH USA

Europe — EMA

Paracetamol B. Braun

GNH USA supplies Paracetamol B. Braun (Paracetamol), a proven analgesic and antipyretic administered intravenously for rapid pain relief and fever reduction

Paracetamol

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What is Paracetamol?

Paracetamol, the active ingredient in Paracetamol B. Braun, is an analgesic, antipyretic presented as an intravenous solution for intravenous use. It is employed to manage moderate to severe pain and to lower elevated body temperature in postoperative or acute care settings, particularly when oral administration is not feasible. The formulation allows rapid onset of action and is suitable for use in hospital wards, intensive care units, and emergency departments.

GNH USA supplies Paracetamol B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

What is Paracetamol used for?

Paracetamol B. Braun is used for pain and fever management in acute care settings.

Pain relief: provides analgesia for moderate to severe pain. Fever reduction: lowers elevated body temperature. Postoperative pain: controls pain after surgical procedures. Acute musculoskeletal pain: alleviates pain from injuries. Headache: reduces intensity of headache episodes.

What are the side effects of Paracetamol?

Paracetamol administered intravenously may be associated with several adverse reactions.

Common Side Effects: - Injection site pain: mild discomfort at the infusion site. - Nausea: transient feeling of queasiness. - Transient hypotension: brief drop in blood pressure.

Serious or Rare Side Effects: - Anaphylaxis: severe allergic reaction with airway compromise. - Hepatotoxicity: significant liver injury, especially with overdose. - Stevens‑Johnson syndrome: rare severe skin reaction.

What precautions apply to Paracetamol?

Paracetamol B. Braun requires careful clinical consideration before use.

Assess liver function: evaluate hepatic enzymes prior to therapy. Avoid in severe hepatic impairment: contraindicated in patients with known liver disease. Monitor blood pressure: watch for hypotension during infusion. Use caution in renal dysfunction: adjust dosing if needed. Avoid concomitant hepatotoxic drugs: limit use with other liver‑affecting agents. Store at ambient temperature: keep in original container, protect from moisture and light.

What does Paracetamol interact with?

Paracetamol B. Braun may interact with other medicines; monitoring is advised.

Major Interactions (Avoid): - Concurrent use with other hepatotoxic agents: increased risk of liver injury. - Alcohol consumption: potentiates hepatic toxicity. - Warfarin: may enhance anticoagulant effect.

Moderate Interactions (Monitor Closely): - CYP450 inducers (e.g., rifampicin): may reduce efficacy. - Antiepileptic drugs (e.g., carbamazepine): may alter metabolism. - Oral contraceptives: may increase risk of liver enzyme elevation.

Frequently asked questions

What is Paracetamol B. Braun used for?+
Paracetamol B. Braun is an intravenous formulation used in hospitals to provide rapid analgesic relief for moderate to severe pain and to reduce fever in patients where oral administration is unsuitable, such as postoperative or critically ill individuals.
How does paracetamol work?+
Paracetamol works by inhibiting cyclooxygenase enzymes, mainly COX‑2, which decreases the production of prostaglandins. Lower prostaglandin levels reduce pain signaling in the nervous system and reset the hypothalamic temperature set‑point, producing analgesic and antipyretic effects.
What is the usual dose of Paracetamol B. Braun?+
The appropriate dose is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and severity of pain or fever. Dosing guidelines are provided in the product’s prescribing information and should be individualized for each patient.
Is Paracetamol B. Braun safe in pregnancy or breastfeeding?+
Data on intravenous paracetamol use during pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made in consultation with a healthcare professional.
How do I order Paracetamol B. Braun from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.
How does Paracetamol B. Braun compare with other analgesics?+
Compared with intravenous non‑steroidal anti‑inflammatory drugs such as ibuprofen, paracetamol has a lower risk of gastrointestinal irritation and platelet inhibition, but it relies on hepatic metabolism and therefore requires careful use in patients with liver dysfunction.
What are the storage and handling requirements for Paracetamol B. Braun?+
Paracetamol B. Braun should be stored at ambient temperature, preferably below 25 °C. Keep the vials in their original packaging, protect them from moisture and direct light, and avoid freezing. Inspect the solution for particulate matter before administration.
How is Paracetamol B. Braun administered?+
The product is given by intravenous infusion. The prescribed volume is diluted in an appropriate compatible IV fluid and administered over the time period recommended in the prescribing information, typically ranging from a few minutes to an hour, depending on clinical need.
What are the most serious risks associated with Paracetamol B. Braun?+
Serious risks include anaphylactic reactions, severe liver injury (hepatotoxicity) especially with overdose or pre‑existing liver disease, and rare severe skin reactions such as Stevens‑Johnson syndrome. Immediate medical attention is required if any of these events occur.
Who should not use Paracetamol B. Braun?+
Paracetamol B. Braun is contraindicated in patients with known hypersensitivity to paracetamol or any excipients, and it should be avoided in individuals with severe hepatic impairment or active liver disease. Caution is also advised for patients with renal dysfunction or those taking other hepatotoxic medications.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Paracetamol
Route
Intravenous Use
Manufacturer
B.Braun Melsungen Ag
Origin
EU

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