GNH USA

Europe — EMA

Paracetamol B. Braun

GNH USA supplies Paracetamol B. Braun (Paracetamol), an analgesic/antipyretic for pain relief and fever reduction, available in sterile injectable form

Paracetamol

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What is Paracetamol?

Paracetamol, the active ingredient in Paracetamol B. Braun, is an analgesic presented as an injectable solution for intravenous use. It treats pain and fever in adult and pediatric patients as directed by a healthcare professional. Paracetamol works by inhibiting central cyclooxygenase enzymes, reducing prostaglandin synthesis and providing symptomatic relief.

GNH USA supplies Paracetamol B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Paracetamol used for?

Paracetamol is an analgesic/antipyretic that reduces pain and fever by acting on the central nervous system.

- Pain relief: provides symptomatic relief of mild to moderate pain. - Fever reduction: lowers elevated body temperature. - Post‑operative pain: helps manage discomfort after surgical procedures. - Headache: alleviates tension‑type and migraine‑associated headache. - Dental pain: reduces discomfort associated with dental procedures.

What are the side effects of Paracetamol?

Paracetamol may cause adverse reactions ranging from mild to severe.

Common Side Effects: - Injection site pain: discomfort at the site of intravenous administration. - Nausea: mild gastrointestinal upset. - Dizziness: transient feeling of light‑headedness. - Flushing: temporary reddening of the skin.

Serious or Rare Side Effects: - Anaphylaxis: severe allergic reaction requiring immediate medical attention. - Severe hepatic injury: potential liver damage, especially with overdose. - Stevens‑Johnson syndrome: rare but serious skin reaction. - Blood dyscrasias: abnormal blood cell counts. - Thrombophlebitis: inflammation of a vein with clot formation.

What precautions apply to Paracetamol?

When using Paracetamol B. Braun, consider the following precautions.

- Hepatic impairment: adjust dose or avoid in patients with severe liver disease. - Renal impairment: use with caution in patients with reduced kidney function. - Allergic reactions: monitor for signs of hypersensitivity, especially in patients with known paracetamol allergy. - Concomitant paracetamol products: avoid duplicate therapy to prevent overdose. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake the vial.

What does Paracetamol interact with?

Paracetamol can interact with several medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid): - Other paracetamol‑containing products: risk of cumulative overdose. - Hepatotoxic drugs (e.g., isoniazid, valproate): increased risk of liver injury. - Warfarin: may potentiate anticoagulant effect and raise INR.

Moderate Interactions (Monitor Closely): - Alcohol consumption: enhances hepatic toxicity. - CYP450 inducers (e.g., carbamazepine, rifampicin): may reduce paracetamol efficacy. - Certain anticonvulsants (e.g., phenytoin): may alter metabolism and require monitoring.

Frequently asked questions

What is Paracetamol B. Braun used for?+
Paracetamol B. Braun is an intravenous formulation of paracetamol used to provide rapid relief of mild to moderate pain and to reduce fever in hospital settings. It is commonly employed after surgery, for headache, dental pain, and other acute pain conditions where oral administration is not feasible.
How does paracetamol work?+
Paracetamol works by inhibiting cyclooxygenase enzymes, especially COX‑2, within the central nervous system. This inhibition reduces the production of prostaglandins, which are mediators of pain and fever, thereby providing analgesic and antipyretic effects without significant anti‑inflammatory activity.
What is the usual dose of Paracetamol B. Braun?+
The dose of Paracetamol B. Braun is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and liver function. Healthcare professionals follow established dosing guidelines and adjust the regimen as needed for safety and efficacy.
Is Paracetamol B. Braun safe in pregnancy or breastfeeding?+
Safety data for intravenous paracetamol during pregnancy and lactation are limited. It should only be used when the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.
How do I order Paracetamol B. Braun from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and required import documentation.
How does Paracetamol B. Braun compare with other IV analgesics?+
Compared with other intravenous analgesics such as ibuprofen or opioid preparations, paracetamol offers effective pain and fever control with a lower risk of gastrointestinal irritation and respiratory depression. It is often used as part of multimodal analgesia to reduce opioid requirements.
What are the storage and handling requirements for Paracetamol B. Braun?+
Paracetamol B. Braun must be stored refrigerated at 2‑8 °C, protected from light, and must not be frozen or shaken. The vial should be kept in its original packaging until use to maintain sterility and stability.
How is Paracetamol B. Braun administered?+
The product is administered by a qualified healthcare professional as an intravenous injection. It may be given undiluted or diluted in compatible IV fluids, following aseptic technique and the prescribed infusion rate.
What are the most serious risks associated with Paracetamol B. Braun?+
Serious risks include severe allergic reactions such as anaphylaxis, rare skin conditions like Stevens‑Johnson syndrome, and potential liver injury, especially with overdose or in patients with pre‑existing hepatic impairment. Prompt medical attention is required if any of these occur.
Who should not use Paracetamol B. Braun?+
Paracetamol B. Braun should be avoided in individuals with known hypersensitivity to paracetamol or any excipients in the formulation, and in patients with severe liver disease. Caution is also advised for those with significant renal impairment or a history of severe allergic reactions to injectable medications.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Paracetamol
Route
Intravenous Use
Manufacturer
B.Braun Melsungen Ag
Origin
EU

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