GNH USA

Europe — EMA

Paracetamol Aurobindo

GNH USA supplies Paracetamol Aurobindo (Paracetamol), an analgesic and antipyretic for pain relief and fever reduction. Request a quote for global supply.

Paracetamol

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What is Paracetamol?

Paracetamol, the active ingredient in Paracetamol Aurobindo, is an analgesic and antipyretic presented as a rectal suppository for systemic use. It provides pain relief and fever reduction for adults and children when administered according to professional guidance.

GNH USA supplies Paracetamol Aurobindo as a licensed, GDP‑compliant international pharmaceutical product, sourced from the European Union and distributed to hospitals, pharmacies and clinics worldwide, adhering to stringent quality and regulatory standards. The company supports global procurement with reliable logistics and regulatory assistance.

What is Paracetamol used for?

Paracetamol acts as an analgesic and antipyretic, reducing pain and fever through central prostaglandin inhibition.

- Mild to moderate pain: provides relief of headache, musculoskeletal discomfort, and postoperative pain. - Fever: lowers elevated body temperature in febrile illnesses. - Dental pain: alleviates pain associated with dental procedures.

What are the side effects of Paracetamol?

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Local irritation: mild discomfort at the site of insertion. - Nausea: occasional feeling of queasiness. - Dizziness: transient light‑headedness. - Rectal bleeding: uncommon irritation leading to minor bleeding.

Serious or Rare Side Effects: - Allergic reaction: rash, itching, swelling, or anaphylaxis. - Hepatotoxicity: elevated liver enzymes or liver injury with overdose. - Blood disorders: rare cases of agranulocytosis or thrombocytopenia. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.

What precautions apply to Paracetamol?

When using Paracetamol Aurobindo, consider the following safety measures.

- Dosage adjustment: reduce dose in patients with hepatic impairment. - Age considerations: use with caution in children under 2 years. - Concurrent illness: avoid in severe liver disease. - Allergy check: confirm no hypersensitivity to paracetamol or excipients. - Pregnancy and lactation: consult a healthcare professional before use. - Store at below 25°C: keep in the original packaging, protect from moisture and heat.

What does Paracetamol interact with?

Paracetamol may interact with other medicines; awareness of major and moderate interactions helps ensure safety.

Major Interactions (Avoid): - Warfarin: concurrent use can increase bleeding risk. - Other paracetamol‑containing products: combined use raises risk of hepatotoxicity. - Alcohol: concurrent consumption heightens liver toxicity.

Moderate Interactions (Monitor Closely): - Enzyme‑inducing antiepileptics (e.g., carbamazepine, phenytoin): may lower plasma levels of paracetamol. - Isoniazid: combined use may increase risk of liver injury.

Frequently asked questions

What is Paracetamol Aurobindo used for?+
Paracetamol Aurobindo is a rectal suppository that provides analgesic and antipyretic effects. It is used to relieve mild to moderate pain such as headaches, musculoskeletal discomfort, and dental pain, and to lower elevated body temperature in febrile conditions.
How does paracetamol work in the body?+
Paracetamol works by inhibiting central cyclooxygenase enzymes, primarily COX‑2, which reduces the synthesis of prostaglandins that mediate pain and fever. This central action produces analgesia and antipyresis without significant peripheral anti‑inflammatory activity.
What is the usual dose of Paracetamol Aurobindo?+
The appropriate dose of Paracetamol Aurobindo is determined by a qualified prescriber based on the patient’s age, weight, clinical condition, and hepatic function. The product is supplied without a fixed dosing regimen, and the healthcare professional will provide specific instructions.
Is Paracetamol Aurobindo safe during pregnancy or breastfeeding?+
Safety in pregnancy and lactation should be evaluated by a healthcare professional. Paracetamol is generally considered compatible with short‑term use during pregnancy and breastfeeding, but the prescriber will weigh potential benefits against any risks before recommending it.
How do I order Paracetamol Aurobindo from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and import documentation.
How does Paracetamol Aurobindo compare with other analgesics?+
Paracetamol Aurobindo offers analgesic and antipyretic activity without the gastrointestinal irritation associated with non‑steroidal anti‑inflammatory drugs (NSAIDs). Compared with opioid analgesics, it has a lower risk of dependence and sedation, making it suitable for mild to moderate pain when a non‑opioid option is preferred.
What are the storage requirements for Paracetamol Aurobindo?+
Paracetamol Aurobindo suppositories should be stored at temperatures below 25 °C, in their original packaging, protected from moisture and direct sunlight. Maintaining these conditions preserves product stability and efficacy throughout its shelf life.
How is Paracetamol Aurobindo administered?+
The suppository is inserted rectally, preferably after a bowel movement and before lying down. The patient should lie on the left side with knees drawn toward the chest to facilitate insertion, and remain in that position for a few minutes to ensure proper absorption.
What are the most serious risks associated with Paracetamol Aurobindo?+
Serious risks include severe allergic reactions such as anaphylaxis, and hepatotoxicity that can occur with overdose or when combined with other paracetamol‑containing products, alcohol, or liver‑impairing conditions. Prompt medical attention is required if signs of liver injury or severe hypersensitivity appear.
Who should not use Paracetamol Aurobindo?+
Paracetamol Aurobindo should be avoided in individuals with known hypersensitivity to paracetamol or any excipients in the suppository, in patients with severe hepatic impairment, and in children under the age recommended by the prescriber. Consultation with a healthcare professional is essential before use in these groups.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Paracetamol
Route
Rectal Use
Manufacturer
Aurobindo Pharma B.V.
Origin
EU

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