Europe — EMA
Paracetamol Arrow
GNH USA supplies Paracetamol Arrow (Paracetamol), a analgesic and antipyretic for fever, headache and mild pain. Request a quote for global supply.
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What is Paracetamol?
Paracetamol, the active ingredient in Paracetamol Arrow, is an analgesic presented as a 500 mg tablet for oral use. It relieves mild to moderate pain and reduces fever in adults and children when appropriate.
GNH USA supplies Paracetamol Arrow as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol used for?
Paracetamol acts as a centrally acting analgesic and antipyretic.
- Fever: Reduces elevated body temperature in acute febrile states. - Headache: Alleviates tension‑type and mild migraine‑related head pain. - Musculoskeletal pain: Provides relief from back, joint and muscle aches. - Dental pain: Helps control pain following dental procedures. - Cold/flu symptoms: Eases discomfort associated with common cold and influenza.
What are the side effects of Paracetamol?
Paracetamol is generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: Mild stomach upset after ingestion. - Abdominal discomfort: Transient pain or fullness. - Rash: Skin redness or mild itching. - Elevated liver enzymes: Minor, often reversible changes.
Serious or Rare Side Effects: - Hepatotoxicity: Severe liver injury, especially with overdose or chronic high use. - Stevens‑Johnson syndrome: Rare severe skin reaction. - Blood dyscrasias: Aplastic anemia or thrombocytopenia. - Anaphylaxis: Immediate hypersensitivity requiring emergency care.
What precautions apply to Paracetamol?
Paracetamol should be used with awareness of specific safety considerations.
- Liver disease: Avoid or limit use in patients with hepatic impairment. - Alcohol consumption: Limit intake as combined use increases hepatotoxic risk. - Age restrictions: Use lower doses for children; follow pediatric guidelines. - Pregnancy and lactation: Use only when clearly needed and prescribed by a healthcare professional. - Overdose risk: Do not exceed recommended daily maximum; monitor concurrent products containing paracetamol. - Store at room temperature below 25°C: keep in the original pack, protect from moisture.
What does Paracetamol interact with?
Paracetamol may interact with several medicines, requiring attention to dosage and monitoring.
Major Interactions (Avoid): - Warfarin: Paracetamol can potentiate anticoagulant effect, increasing bleeding risk. - Alcohol: Combined use heightens risk of liver injury. - Carbamazepine: Enzyme induction may reduce paracetamol efficacy.
Moderate Interactions (Monitor Closely): - Isoniazid: May increase risk of liver toxicity. - Phenytoin: May alter paracetamol metabolism, requiring dose adjustment. - Rifampicin: Can increase hepatic clearance, potentially lowering therapeutic effect.
