Europe — EMA
Paracetamol And Caffeine Nevik (Paracetamol, Caffeine)
GNH USA supplies Paracetamol And Caffeine Nevik (Paracetamol, Caffeine), an analgesic/antipyretic for headache, fever and mild pain.
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What is Paracetamol, Caffeine?
Paracetamol, the active ingredient in Paracetamol And Caffeine Nevik, is an analgesic presented as a tablet for oral use. It is used to relieve mild to moderate pain and reduce fever in adults and children when appropriate. Paracetamol works together with caffeine, a central nervous system stimulant, to enhance analgesic effect.
GNH USA supplies Paracetamol And Caffeine Nevik as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol, Caffeine used for?
Paracetamol and caffeine act as an analgesic and antipyretic, targeting common pain and fever pathways. - Headache: Reduces pain intensity and associated discomfort. - Fever: Lowers elevated body temperature in acute febrile states. - Musculoskeletal pain: Alleviates mild to moderate aches such as backache or toothache. - Menstrual discomfort: Diminishes cramping pain and associated headache. - Cold‑related symptoms: Relieves headache and fever accompanying upper respiratory infections.
What are the side effects of Paracetamol, Caffeine?
Paracetamol and caffeine are generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: Mild stomach upset or queasiness. - Insomnia: Difficulty falling or staying asleep. - Restlessness: Feeling jittery or uneasy. - Increased heart rate: Palpitations or tachycardia. - Gastro‑intestinal discomfort: Stomach pain or dyspepsia. - Headache rebound: Occasional worsening of headache after use.
Serious or Rare Side Effects: - Allergic reactions: Rash, itching, swelling, or anaphylaxis. - Hepatic injury: Elevated liver enzymes or liver failure, especially with overdose. - Stevens‑Johnson syndrome: Severe skin blistering and mucosal involvement. - Blood disorders: Thrombocytopenia or neutropenia. - Cardiovascular events: Hypertension or arrhythmia in susceptible individuals. - Severe gastrointestinal bleeding: Rare but possible with concomitant anticoagulants.
What precautions apply to Paracetamol, Caffeine?
Paracetamol and caffeine should be used with awareness of individual health status and potential risks. - Liver function: Avoid use in patients with severe hepatic impairment. - Pregnancy: Use only if clearly needed and prescribed by a healthcare professional. - Breastfeeding: Consider potential transfer to infant; consult a clinician. - Cardiovascular disease: Caution in patients with hypertension or arrhythmias. - Drug interactions: Review concomitant medications for possible interactions. - Store at ambient temperature: Keep below 25 °C, in the original packaging, protected from moisture and direct sunlight.
What does Paracetamol, Caffeine interact with?
Paracetamol and caffeine may interact with several medicines; monitoring is advised.
Major Interactions (Avoid): - Warfarin: Paracetamol can potentiate anticoagulant effect, increasing bleeding risk. - Carbamazepine: Induces metabolism, reducing paracetamol efficacy. - Monoamine oxidase inhibitors (MAOIs): Caffeine may cause hypertensive episodes.
Moderate Interactions (Monitor Closely): - Oral contraceptives: Paracetamol may increase hepatic enzyme activity, reducing contraceptive effectiveness. - Antiepileptic drugs (e.g., phenytoin): May alter caffeine clearance. - Lithium: Caffeine can increase lithium excretion, affecting serum levels.



