Europe — EMA
Paracetamol Accord
GNH USA supplies Paracetamol Accord (Paracetamol), an analgesic/antipyretic for pain relief and fever reduction. Request a quote for global supply.
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What is Paracetamol?
Paracetamol, the active ingredient in Paracetamol Accord, is an analgesic presented as a 500 mg tablet for oral use. It relieves mild to moderate pain and reduces fever in adults and children. GNH USA supplies Paracetamol Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
GNH USA supplies Paracetamol Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol used for?
Paracetamol Accord is an analgesic and antipyretic that acts on pain‑related and febrile pathways.
- Headache: provides relief from tension‑type and mild migraine pain. - Fever: lowers elevated body temperature in infectious or inflammatory states. - Musculoskeletal pain: eases aches associated with back strain, sprains and minor arthritis. - Dental pain: reduces discomfort following dental procedures or toothache. - Post‑operative pain: helps manage mild pain after minor surgical interventions.
What are the side effects of Paracetamol?
Paracetamol is generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: mild stomach upset may be experienced. - Rash: occasional skin redness or itching. - Elevated liver enzymes: transient increase detected in blood tests. - Headache: paradoxical headache in a small number of users.
Serious or Rare Side Effects: - Stevens‑Johnson syndrome: severe skin reaction requiring immediate medical attention. - Acute liver failure: risk increases with overdose or chronic high‑dose use. - Anaphylaxis: rare allergic reaction with breathing difficulty. - Blood dyscrasias: rare blood‑cell abnormalities such as agranulocytosis.
What precautions apply to Paracetamol?
Paracetamol should be used with awareness of specific safety considerations.
- Dose limitation: do not exceed the maximum daily amount recommended by a healthcare professional. - Liver disease: avoid use or seek medical advice if you have hepatic impairment. - Alcohol use: limit alcohol consumption while taking the product to reduce liver stress. - Pregnancy: consult a healthcare provider before use during pregnancy or breastfeeding. - Drug interactions: review all concurrent medications with a pharmacist or physician. - Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.
What does Paracetamol interact with?
Paracetamol can interact with several medicines, requiring attention to dosage and monitoring.
Major Interactions (Avoid): - Warfarin: may increase anticoagulant effect and bleeding risk. - Isoniazid: can potentiate liver toxicity when combined.
Moderate Interactions (Monitor Closely): - Antiepileptic drugs (e.g., carbamazepine, phenytoin): may reduce paracetamol plasma levels. - Rifampicin: may increase metabolic clearance, lowering efficacy. - Oral contraceptives: may slightly decrease analgesic effectiveness. - High‑dose vitamin C: may enhance hepatic metabolism, affecting safety.
