GNH USA

Europe — EMA

Paracetamol Accord

GNH USA supplies Paracetamol Accord (Paracetamol), a non‑opioid analgesic and antipyretic for fever, pain and headache relief.

Paracetamol

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What is Paracetamol?

Paracetamol, the active ingredient in Paracetamol Accord, is a non‑opioid analgesic and antipyretic presented as a 500 mg tablet for oral use. It relieves mild to moderate pain and reduces fever in adults and children.

GNH USA supplies Paracetamol Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Paracetamol used for?

Paracetamol acts by inhibiting prostaglandin synthesis, providing relief for a range of common pain and fever conditions. - Fever: reduces elevated body temperature associated with infections or inflammatory processes. - Headache: alleviates tension‑type and mild migraine‑related head pain. - Musculoskeletal pain: eases aches from strains, sprains or over‑exertion. - Dental pain: mitigates discomfort following dental procedures. - Cold and flu symptoms: helps control fever and body aches accompanying viral upper‑respiratory infections.

What are the side effects of Paracetamol?

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea: mild stomach upset that resolves with continued use. - Headache: occasional worsening of existing headache. - Skin rash: mild erythema or itching. - Abdominal discomfort: transient stomach pain. - Elevated liver enzymes: mild, usually reversible.

Serious or Rare Side Effects: - Severe allergic reactions: anaphylaxis, angioedema, or urticaria. - Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Hepatotoxicity: acute liver injury, especially with overdose. - Blood disorders: agranulocytosis or thrombocytopenia.

What precautions apply to Paracetamol?

Paracetamol should be used with awareness of several safety considerations. - Liver function: avoid or limit use in patients with severe hepatic impairment. - Alcohol consumption: limit intake as combined use increases risk of liver damage. - Maximum daily dose: do not exceed the recommended total daily amount for adults. - Pregnancy and breastfeeding: use only under medical guidance, especially in the first trimester. - Pediatric use: select age‑appropriate formulations and follow prescriber instructions. - Store below 25°C: keep in the original pack, protect from moisture.

What does Paracetamol interact with?

Paracetamol can interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid): - Warfarin: may increase anticoagulant effect and bleeding risk. - Alcohol: synergistic hepatotoxic potential.

Moderate Interactions (Monitor Closely): - Carbamazepine: may reduce paracetamol plasma levels. - Isoniazid: can heighten risk of liver injury. - Oral contraceptives: may slightly lower contraceptive efficacy.

Frequently asked questions

What is Paracetamol Accord used for?+
Paracetamol Accord is used to relieve mild to moderate pain such as headaches, musculoskeletal aches, dental discomfort, and to reduce fever associated with infections or inflammatory conditions. It provides symptomatic relief without significant anti‑inflammatory activity.
How does paracetamol work?+
Paracetamol works by reversibly inhibiting cyclooxygenase enzymes, mainly COX‑2, in the central nervous system. This reduces the production of prostaglandins that signal pain and raise body temperature, resulting in analgesic and antipyretic effects.
What is the usual dose of Paracetamol Accord?+
The appropriate dose of Paracetamol Accord is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and overall health status. Patients should follow the prescriber’s instructions and not exceed the recommended daily maximum.
Is Paracetamol Accord safe during pregnancy or breastfeeding?+
Paracetamol is generally considered safe for short‑term use during pregnancy and lactation when prescribed by a qualified clinician. However, it should be used only under medical advice, especially in the first trimester, and the lowest effective dose should be chosen.
How do I order Paracetamol Accord from GNH USA?+
To order Paracetamol Accord, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Paracetamol Accord compare with other pain relievers?+
Paracetamol differs from non‑steroidal anti‑inflammatory drugs (NSAIDs) by lacking significant peripheral anti‑inflammatory activity and having a lower risk of gastrointestinal irritation. Compared with opioids, it does not cause dependence or respiratory depression, making it suitable for mild to moderate pain.
What are the storage and handling requirements for Paracetamol Accord?+
Paracetamol Accord should be stored below 25 °C in a dry place, protected from moisture and direct sunlight. Keep the tablets in their original packaging until use to maintain stability and potency.
How is Paracetamol Accord administered?+
Paracetamol Accord is taken orally, usually with a glass of water. The tablet should be swallowed whole and not crushed or chewed unless a specific formulation permits it. Administration should follow the prescriber’s dosing schedule.
What are the most serious risks associated with Paracetamol Accord?+
The most serious risks include severe liver injury (hepatotoxicity) especially with overdose, and rare but life‑threatening allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome. Prompt medical attention is required if signs of liver dysfunction or severe rash appear.
Who should not use Paracetamol Accord?+
Paracetamol Accord should be avoided by individuals with known hypersensitivity to paracetamol, severe hepatic impairment, or those who regularly consume excessive alcohol. It should also be used with caution in patients with chronic liver disease or those taking interacting medications.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Paracetamol
Route
Intravenous Use
Manufacturer
Accord Healthcare Limited
Origin
EU

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