Paracetamol Accord

Paracetamol, the active ingredient in Paracetamol Accord, is an analgesic/antipyretic presented as an oral tablet for oral use. It provides relief from mild to moderate pain and reduces fever in adults and children.\n\nGNH India supplies Paracetamol Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Paracetamol is an analgesic and antipyretic that reduces pain and fever by acting on the central nervous system.\n\n- Mild to moderate pain: provides relief from headaches, musculoskeletal discomfort, dental pain and other common aches.\n- Fever: lowers elevated body temperature associated with infections, inflammatory conditions or other causes.\n- Cold and flu symptoms: alleviates associated aches, sore throat discomfort and fever during upper respiratory infections.

Paracetamol is generally well tolerated, but adverse reactions can occur.\n\nCommon Side Effects:\n- Nausea: mild stomach upset that may accompany dosing.\n- Skin rash: occasional mild erythema or itching.\n- Elevated liver enzymes: transient increases detectable in laboratory tests.\n- Headache: paradoxical headache in a small number of users.\n\nSerious or Rare Side Effects:\n- Hepatotoxicity: severe liver injury, especially with overdose or chronic high‑dose use.\n- Stevens‑Johnson syndrome: rare severe skin reaction requiring immediate medical attention.\n- Anaphylaxis: extremely rare allergic reaction with breathing difficulty and swelling.

Paracetamol should be used with awareness of specific safety considerations.\n\n- Dose limitation: do not exceed the maximum daily amount recommended by a healthcare professional.\n- Liver disease: avoid or use only under strict medical supervision if hepatic impairment is present.\n- Alcohol consumption: limit intake as concurrent alcohol use can increase liver toxicity risk.\n- Pregnancy: consult a physician; generally considered safe when prescribed, but professional guidance is essential.\n- Pediatric use: ensure appropriate formulation and dosing for children; follow prescriber instructions.\n- Store at ambient temperature: keep below 25°C, retain in original packaging, protect from moisture and direct sunlight.

Paracetamol may interact with other medicines, altering its efficacy or safety profile.\n\nMajor Interactions (Avoid):\n- Warfarin: increased anticoagulant effect may raise bleeding risk.\n- High‑dose ibuprofen or other NSAIDs: combined use can heighten liver toxicity.\n\nModerate Interactions (Monitor Closely):\n- Antiepileptic drugs (e.g., carbamazepine, phenytoin): may reduce paracetamol plasma levels.\n- Rifampicin: may increase metabolism, lowering effectiveness.\n- Alcohol: chronic consumption can potentiate hepatotoxicity.