GNH USA

Europe — EMA

Paracetamol Accord

GNH USA supplies Paracetamol Accord (Paracetamol), a analgesic, antipyretic for pain and fever. Request a quote for global supply. available worldwide.

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What is Paracetamol?

Paracetamol, the active ingredient in Paracetamol Accord, is an analgesic, antipyretic presented as an intravenous solution for intravenous use. It treats pain and fever in adults and children when prescribed by a healthcare professional.

GNH USA supplies Paracetamol Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Paracetamol used for?

Paracetamol is an analgesic and antipyretic that reduces discomfort and temperature elevation associated with various conditions.

- Pain: provides relief from mild to moderate acute pain. - Fever: lowers elevated body temperature. - Post‑operative pain: helps manage pain after surgical procedures. - Dental pain: alleviates discomfort following dental work.

What are the side effects of Paracetamol?

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea: mild stomach upset. - Rash: skin redness or itching. - Elevated liver enzymes: transient increase in laboratory values. - Headache: occasional mild headache. - Injection site pain: discomfort at the IV site.

Serious or Rare Side Effects: - Anaphylaxis: severe allergic reaction requiring immediate medical attention. - Stevens‑Johnson syndrome: rare severe skin reaction. - Hepatotoxicity: potential liver injury, especially with overdose. - Blood dyscrasias: rare blood cell abnormalities. - Severe hypotension: abrupt drop in blood pressure during infusion.

What precautions apply to Paracetamol?

Paracetamol should be used with caution in specific clinical situations. - Liver disease: avoid or adjust dose in patients with impaired hepatic function. - Alcohol use: limit intake as combined use may increase liver risk. - Renal impairment: monitor kidney function in patients with chronic kidney disease. - Concomitant hepatotoxic drugs: avoid simultaneous use with other liver‑affecting medications. - Allergy history: assess for prior hypersensitivity to paracetamol or excipients. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Paracetamol interact with?

Paracetamol may interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid): - Warfarin: increased risk of bleeding. - Carbamazepine: enhanced hepatotoxic potential. - Rifampicin: may reduce paracetamol effectiveness.

Moderate Interactions (Monitor Closely): - Alcohol: additive liver stress. - Isoniazid: potential for liver enzyme elevation. - Phenobarbital: may increase metabolism, reducing analgesic effect.

Frequently asked questions

What is Paracetamol Accord used for?+
Paracetamol Accord is an intravenous formulation of paracetamol used to relieve mild to moderate pain and to reduce fever in hospital settings. It is administered by healthcare professionals when rapid onset of analgesia or antipyresis is required.
How does paracetamol work?+
Paracetamol acts by inhibiting cyclooxygenase enzymes in the central nervous system, which lowers prostaglandin production. This reduction diminishes pain signaling and resets the hypothalamic temperature set‑point, providing both analgesic and antipyretic effects.
What is the usual dose of Paracetamol Accord?+
The dosage of Paracetamol Accord is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and renal or hepatic function. No fixed regimen is provided here; the prescriber sets the appropriate dose.
Is Paracetamol Accord safe during pregnancy or breastfeeding?+
Paracetamol is generally considered compatible with pregnancy and lactation when used at recommended doses, but safety information for the intravenous formulation is limited. Clinicians should evaluate the risk‑benefit ratio for each patient and follow local guidelines.
How do I order Paracetamol Accord from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifying trade or institutional credentials before providing pricing, availability, shipping details (including cold‑chain where needed), and import documentation.
How does Paracetamol Accord compare with other analgesics?+
Compared with non‑steroidal anti‑inflammatory drugs (NSAIDs), paracetamol provides analgesia and antipyresis without significant anti‑inflammatory activity or gastrointestinal irritation. Unlike opioids, it carries no risk of respiratory depression or dependence, making it a preferred option for mild to moderate pain when rapid effect is desired.
What are the storage and handling requirements for Paracetamol Accord?+
Paracetamol Accord should be stored at 2‑8 °C, protected from light, and must not be frozen or shaken. Keep the solution in its original packaging until use, and discard any product that appears discolored or contains particles.
How is Paracetamol Accord administered?+
Paracetamol Accord is given by intravenous infusion under the supervision of qualified medical staff. The infusion rate and volume are set by the prescriber, and the solution should be administered using aseptic technique to avoid contamination.
What are the most serious risks associated with Paracetamol Accord?+
The most serious risks include severe allergic reactions such as anaphylaxis, rare skin conditions like Stevens‑Johnson syndrome, and hepatotoxicity, especially in cases of overdose or pre‑existing liver disease. Prompt medical attention is required if any of these symptoms arise.
Who should not use Paracetamol Accord?+
Paracetamol Accord should be avoided in patients with known hypersensitivity to paracetamol or any excipients in the formulation, in those with severe hepatic impairment, and in individuals who have experienced serious adverse reactions to paracetamol in the past.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Paracetamol
Route
Intravenous Use
Manufacturer
Accord Healthcare Polska Sp. Z O.O.
Origin
EU

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