Europe — EMA
Paracetamol Accord
GNH USA supplies Paracetamol Accord (Paracetamol), a analgesic, antipyretic for pain and fever. Request a quote for global supply. available worldwide.
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What is Paracetamol?
Paracetamol, the active ingredient in Paracetamol Accord, is an analgesic, antipyretic presented as an intravenous solution for intravenous use. It treats pain and fever in adults and children when prescribed by a healthcare professional.
GNH USA supplies Paracetamol Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol used for?
Paracetamol is an analgesic and antipyretic that reduces discomfort and temperature elevation associated with various conditions.
- Pain: provides relief from mild to moderate acute pain. - Fever: lowers elevated body temperature. - Post‑operative pain: helps manage pain after surgical procedures. - Dental pain: alleviates discomfort following dental work.
What are the side effects of Paracetamol?
Paracetamol is generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: mild stomach upset. - Rash: skin redness or itching. - Elevated liver enzymes: transient increase in laboratory values. - Headache: occasional mild headache. - Injection site pain: discomfort at the IV site.
Serious or Rare Side Effects: - Anaphylaxis: severe allergic reaction requiring immediate medical attention. - Stevens‑Johnson syndrome: rare severe skin reaction. - Hepatotoxicity: potential liver injury, especially with overdose. - Blood dyscrasias: rare blood cell abnormalities. - Severe hypotension: abrupt drop in blood pressure during infusion.
What precautions apply to Paracetamol?
Paracetamol should be used with caution in specific clinical situations. - Liver disease: avoid or adjust dose in patients with impaired hepatic function. - Alcohol use: limit intake as combined use may increase liver risk. - Renal impairment: monitor kidney function in patients with chronic kidney disease. - Concomitant hepatotoxic drugs: avoid simultaneous use with other liver‑affecting medications. - Allergy history: assess for prior hypersensitivity to paracetamol or excipients. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.
What does Paracetamol interact with?
Paracetamol may interact with other medicines, altering efficacy or safety.
Major Interactions (Avoid): - Warfarin: increased risk of bleeding. - Carbamazepine: enhanced hepatotoxic potential. - Rifampicin: may reduce paracetamol effectiveness.
Moderate Interactions (Monitor Closely): - Alcohol: additive liver stress. - Isoniazid: potential for liver enzyme elevation. - Phenobarbital: may increase metabolism, reducing analgesic effect.



