Europe — EMA
Paracetamol Accord
GNH USA supplies Paracetamol Accord (Paracetamol), a analgesic and antipyretic for pain relief and fever reduction.
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What is Paracetamol?
Paracetamol, the active ingredient in Paracetamol Accord, is an analgesic and antipyretic presented as a tablet for oral use. It relieves mild to moderate pain and reduces fever in adults and children.
GNH USA supplies Paracetamol Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol used for?
Paracetamol is an analgesic and antipyretic used to manage pain and fever across various conditions.
- Headache: provides relief from tension‑type headaches. - Fever: reduces elevated body temperature. - Musculoskeletal pain: alleviates mild to moderate pain from strains or sprains. - Dental pain: eases discomfort after dental procedures. - Cold symptoms: helps control fever and aches associated with the common cold.
What are the side effects of Paracetamol?
Paracetamol is generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: mild stomach upset. - Abdominal discomfort: occasional stomach pain. - Rash: skin redness or itching. - Headache: paradoxical headache in some users.
Serious or Rare Side Effects: - Stevens‑Johnson syndrome: severe skin reaction. - Hepatic failure: liver injury, especially with overdose. - Blood dyscrasias: rare blood cell abnormalities. - Anaphylaxis: life‑threatening allergic reaction.
What precautions apply to Paracetamol?
Paracetamol should be used with attention to specific safety considerations.
- Liver function: avoid use in severe hepatic impairment. - Alcohol consumption: limit alcohol as it may increase liver toxicity. - Dosage limits: do not exceed the recommended total daily dose. - Age restrictions: use lower doses in children according to weight. - Pregnancy and lactation: consult a healthcare professional before use. - Store at ambient temperature: keep in the original pack, protect from moisture and heat.
What does Paracetamol interact with?
Paracetamol can interact with several medicines, requiring monitoring.
Major Interactions (Avoid): - Warfarin: increased anticoagulant effect, risk of bleeding. - Isoniazid: heightened risk of hepatotoxicity. - Carbamazepine: reduced paracetamol clearance, lowering efficacy.
Moderate Interactions (Monitor Closely): - Alcohol: additive liver stress, especially with chronic use. - Phenytoin: may increase hepatic enzyme activity, affecting metabolism. - Phenobarbital: may reduce paracetamol effectiveness through enzyme induction.
