GNH USA

Europe — EMA

Paracetamol 500

GNH USA supplies Paracetamol 500 (Paracetamol), a analgesic, antipyretic for pain and fever, suitable for adult and pediatric use.

Paracetamol

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What is Paracetamol?

Paracetamol, the active ingredient in Paracetamol 500, is an analgesic and antipyretic presented as a 500 mg tablet for oral use. It is used to relieve mild to moderate pain and reduce fever in adults and children, and is commonly available over‑the‑counter for conditions such as headache, toothache, musculoskeletal discomfort, and febrile illnesses.

GNH USA supplies Paracetamol 500 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, following strict quality standards and providing reliable distribution for global healthcare markets.

What is Paracetamol used for?

Paracetamol is an analgesic and antipyretic that reduces pain and fever by acting on the central nervous system.

- Pain: provides relief of mild to moderate pain. - Fever: lowers elevated body temperature. - Headache: alleviates tension‑type headache. - Toothache: reduces dental pain. - Musculoskeletal discomfort: eases aches associated with strain.

What are the side effects of Paracetamol?

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea: mild stomach upset. - Rash: skin redness or itching. - Headache: transient headache. - Dizziness: feeling light‑headed. - Abdominal discomfort: mild stomach pain.

Serious or Rare Side Effects: - Severe skin reactions: such as Stevens‑Johnson syndrome. - Liver toxicity: especially with overdose or pre‑existing liver disease. - Blood disorders: including thrombocytopenia. - Anaphylaxis: rare severe allergic response.

What precautions apply to Paracetamol?

When using Paracetamol, consider the following safety measures.

- Dosage adjustment: reduce dose in patients with hepatic impairment. - Alcohol use: avoid excessive alcohol while taking this medication. - Age: use with caution in children under 2 years of age. - Drug interactions: review concomitant medications for potential interactions. - Allergy: discontinue if hypersensitivity reactions develop. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

What does Paracetamol interact with?

Paracetamol may interact with other medicines; monitor accordingly.

Major Interactions (Avoid): - Alcohol: increased risk of liver injury. - Warfarin: may enhance anticoagulant effect. - Isoniazid: heightened hepatotoxicity.

Moderate Interactions (Monitor Closely): - Carbamazepine: may reduce paracetamol efficacy. - Phenobarbital: may increase paracetamol metabolism.

Frequently asked questions

What is Paracetamol 500 used for?+
Paracetamol 500 is used to relieve mild to moderate pain such as headache, toothache, or muscle aches, and to reduce fever. It is an over‑the‑counter analgesic and antipyretic suitable for adults and children when directed by a healthcare professional.
How does paracetamol work in the body?+
Paracetamol works by inhibiting cyclooxygenase enzymes in the central nervous system, which lowers the production of prostaglandins that mediate pain and regulate body temperature. This results in analgesic and antipyretic effects without significant anti‑inflammatory activity.
What is the usual dose of Paracetamol 500?+
The appropriate dose of Paracetamol 500 is determined by the prescribing healthcare professional based on the patient’s age, weight, and clinical condition. Patients should follow the prescriber’s instructions and not exceed the recommended maximum daily amount.
Is Paracetamol 500 safe during pregnancy or breastfeeding?+
Paracetamol is generally considered compatible with pregnancy and breastfeeding when used at the lowest effective dose for the shortest duration. However, pregnant or nursing individuals should consult their healthcare provider before using the product.
How do I order Paracetamol 500 from GNH USA?+
To order Paracetamol 500, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and import documentation.
How does Paracetamol 500 compare with other pain relievers?+
Paracetamol 500 differs from non‑steroidal anti‑inflammatory drugs (NSAIDs) such as ibuprofen in that it has minimal peripheral anti‑inflammatory activity and a lower risk of gastrointestinal irritation. It is often chosen when NSAIDs are contraindicated or when a simple analgesic/antipyretic is needed.
What are the storage and handling requirements for Paracetamol 500?+
Paracetamol 500 tablets should be stored at ambient temperature, below 25 °C, in their original packaging. Keep the product away from moisture, direct sunlight, and out of reach of children to maintain stability and potency.
How is Paracetamol 500 administered?+
Paracetamol 500 is administered orally, typically as a whole tablet swallowed with water. It may be taken with or without food, according to the prescriber’s guidance, and should be used as directed on the prescription label.
What are the most serious risks associated with Paracetamol 500?+
The most serious risks include severe liver injury, especially with overdose or in patients with existing liver disease, and rare but severe skin reactions such as Stevens‑Johnson syndrome. Prompt medical attention is required if signs of liver dysfunction or serious skin changes occur.
Who should not use Paracetamol 500?+
Paracetamol 500 should be avoided by individuals with known hypersensitivity to paracetamol, severe liver impairment, or those who have experienced serious adverse reactions to the drug. Children under two years of age should only use formulations specifically approved for that age group.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Paracetamol
Route
Oral Use
Manufacturer
1 A Pharma Gmbh
Origin
EU

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