Paracetamol

Paracetamol, the active ingredient in Paracetamol, is an Analgesic presented as an oral tablet for oral use. It provides effective pain relief and reduces fever across a broad patient population, including adults and children, when used according to professional guidance.

GNH USA supplies Paracetamol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality and regulatory conformity for global healthcare providers and reliable product availability across diverse markets.

Paracetamol is an analgesic and antipyretic used to manage common pain and fever conditions.

- Headache: relief of pain associated with tension‑type or migraine headaches. - Fever: reduction of elevated body temperature in infectious or inflammatory states. - Musculoskeletal pain: alleviation of aches and soreness in muscles, joints and back. - Toothache: mitigation of dental pain following procedures or infection.

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea: mild gastrointestinal upset. - Abdominal discomfort: occasional stomach pain. - Rash: mild skin irritation or itching. - Headache: paradoxical headache in some users.

Serious or Rare Side Effects: - Hepatotoxicity: severe liver injury, especially with overdose. - Stevens‑Johnson syndrome or toxic epidermal necrolysis: rare severe skin reactions. - Blood disorders: agranulocytosis or thrombocytopenia in very rare cases.

When using Paracetamol, consider the following safety measures.

- Dose adjustment in liver disease: reduce dose or avoid use in severe hepatic impairment. - Avoid in severe renal impairment: monitor renal function and limit exposure. - Do not exceed recommended daily amount: adhere to maximum 4 g per day for adults. - Use caution with alcohol: concurrent intake may increase liver toxicity risk. - Pregnancy and breastfeeding: consult a healthcare professional before use. - Store at ambient temperature: keep in the original pack, protect from moisture.

Paracetamol may interact with other medicines; monitor as indicated.

Major Interactions (Avoid): - Concurrent use with other hepatotoxic drugs: increased risk of liver injury. - Alcohol consumption: potentiates hepatic toxicity. - Warfarin: may enhance anticoagulant effect and increase bleeding risk.

Moderate Interactions (Monitor Closely): - Carbamazepine: may reduce paracetamol plasma concentrations. - Phenytoin: may decrease analgesic efficacy. - Rifampicin: may increase metabolism leading to lower effectiveness.