GNH USA

Europe — EMA

Paracetamol

GNH USA supplies Paracetamol (Paracetamol), an analgesic and antipyretic widely used for fever, headache, toothache and musculoskeletal pain.

Paracetamol

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What is Paracetamol?

Paracetamol, the active ingredient in Paracetamol, is an analgesic presented as an unknown/unknown for oral use. It treats pain and fever in adults and children, providing relief for common mild to moderate discomfort.\n\nGNH India supplies Paracetamol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Paracetamol used for?

Paracetamol acts as a centrally acting analgesic and antipyretic, reducing pain and fever across several common conditions.\n\n- Fever: Lowers elevated body temperature.\n- Headache: Relieves tension‑type and mild migraine pain.\n- Musculoskeletal pain: Alleviates aches from strains or over‑use.\n- Toothache: Reduces dental pain after procedures.\n- Cold and flu symptoms: Eases associated mild pain and fever.

What are the side effects of Paracetamol?

Paracetamol is generally well tolerated, but adverse reactions can occur.\n\nCommon Side Effects:\n- Nausea\n- Skin rash or mild itching\n- Dizziness\n- Upper abdominal discomfort\n- Elevated liver enzymes (asymptomatic)\n\nSerious or Rare Side Effects:\n- Stevens‑Johnson syndrome or toxic epidermal necrolysis\n- Acute liver failure, especially with overdose\n- Blood dyscrasias such as agranulocytosis\n- Anaphylactic or anaphylactoid reactions\n- Severe skin reactions including drug reaction with eosinophilia and systemic symptoms (DRESS).

What precautions apply to Paracetamol?

Paracetamol should be used with awareness of specific safety considerations.\n\n- Pregnancy: Use only when clearly needed and after medical advice.\n- Liver disease: Avoid or limit use; monitor hepatic function.\n- Alcohol consumption: Limit intake to reduce hepatotoxic risk.\n- Children: Ensure appropriate formulation and dosing by a healthcare professional.\n- Concomitant use with other paracetamol‑containing products: Avoid duplicate therapy.\n- Store at ambient temperature: Keep below 25°C, in the original packaging, protected from moisture and direct sunlight.

What does Paracetamol interact with?

Paracetamol can interact with several medicines, requiring attention to dosage and monitoring.\n\nMajor Interactions (Avoid):\n- Warfarin: May increase anticoagulant effect and bleeding risk.\n- Alcohol: Heightens risk of liver injury.\n- Carbamazepine: May reduce paracetamol plasma levels.\n\nModerate Interactions (Monitor Closely):\n- Isoniazid: Potential for increased hepatotoxicity.\n- Phenobarbital: May enhance hepatic metabolism of paracetamol.\n- Oral contraceptives: May slightly increase hepatic enzyme activity, requiring monitoring.

Frequently asked questions

What conditions is Paracetamol used for?+
Paracetamol is used to relieve mild to moderate pain such as headache, toothache, muscle aches, and to reduce fever associated with common infections or inflammatory conditions. It is a first‑line option for many over‑the‑counter pain‑relief needs.
How does Paracetamol work in the body?+
Paracetamol works by inhibiting central cyclooxygenase enzymes, which reduces the production of prostaglandins that signal pain and raise body temperature. This central action provides analgesic and antipyretic effects without significant anti‑inflammatory activity.
What is the usual dose of Paracetamol?+
The appropriate dose of Paracetamol is determined by a prescriber or according to the product label, based on the patient’s age, weight, and clinical condition. Dosage instructions should always be followed as directed by a healthcare professional.
Is Paracetamol safe during pregnancy or breastfeeding?+
Paracetamol is generally considered safe for short‑term use during pregnancy and lactation when used at recommended doses. However, it should only be taken when clearly needed and under the guidance of a qualified healthcare provider.
How do I order Paracetamol from GNH USA?+
To order Paracetamol, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Paracetamol compare with ibuprofen?+
Paracetamol provides analgesic and antipyretic effects without the anti‑inflammatory activity of ibuprofen. It is gentler on the stomach and does not affect platelet function, making it preferable for patients who need pain relief but cannot tolerate NSAIDs.
What are the storage requirements for Paracetamol?+
Paracetamol should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.
How is Paracetamol administered?+
Paracetamol is administered orally, typically as tablets, capsules, or liquid formulations. It should be taken with or without food, according to the prescribing information, and the dose should be spaced appropriately to avoid exceeding the daily maximum.
What are the most serious risks associated with Paracetamol?+
The most serious risks include severe liver injury, especially with overdose or chronic high‑dose use, and rare hypersensitivity reactions such as Stevens‑Johnson syndrome. Prompt medical attention is required if signs of liver dysfunction or severe skin reactions appear.
Who should not use Paracetamol?+
Paracetamol should be avoided by individuals with known hypersensitivity to the drug, severe liver disease, or those who are regularly consuming high amounts of alcohol. Children under the recommended age or weight limits should not use adult formulations without professional guidance.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Paracetamol
Route
Oral Use
Manufacturer
Crescent Pharma Limited
Origin
EU

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