GNH USA

Europe — EMA

Paracetamol

GNH USA supplies Paracetamol (Paracetamol), a Analgesic for pain and fever, to hospitals, pharmacies and clinics worldwide. Request a quote for global supply.

Paracetamol

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What is Paracetamol?

Paracetamol, the active ingredient in Paracetamol, is an Analgesic presented as a unknown/unknown for Oral use. It relieves pain and reduces fever in adults and children.

GNH USA supplies Paracetamol as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Paracetamol used for?

Paracetamol acts as an analgesic and antipyretic to manage common pain and fever conditions.

Pain: provides relief of mild to moderate pain such as headache, dental or musculoskeletal discomfort. Fever: reduces elevated body temperature associated with infections or inflammatory states. Headache: alleviates tension‑type and migraine‑associated headache pain. Dental pain: eases discomfort after dental procedures or toothache.

What are the side effects of Paracetamol?

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea: mild stomach upset may be reported. - Abdominal discomfort: occasional stomach pain or dyspepsia. - Rash: transient skin redness or mild itching. - Elevated liver enzymes: mild, reversible changes in laboratory tests. - Headache: paradoxical headache in a small subset of users.

Serious or Rare Side Effects: - Hepatotoxicity: severe liver injury, especially with overdose or chronic high‑dose use. - Stevens‑Johnson syndrome or toxic epidermal necrolysis: rare severe skin reactions. - Blood dyscrasias: agranulocytosis or thrombocytopenia reported infrequently. - Anaphylaxis: rare immediate hypersensitivity reaction. - Renal impairment: possible acute kidney injury in susceptible individuals.

What precautions apply to Paracetamol?

Paracetamol should be used with awareness of specific safety considerations. - Assess liver function: avoid use in patients with existing severe hepatic disease. - Limit alcohol intake: concurrent alcohol increases risk of liver toxicity. - Monitor for allergy: discontinue if rash, swelling, or breathing difficulty develop. - Use caution in renal impairment: adjust use in patients with reduced kidney function. - Avoid exceeding recommended daily amount: follow prescriber guidance to prevent overdose. - Store at ambient temperature: keep below 25°C in the original packaging, protect from moisture and direct sunlight.

What does Paracetamol interact with?

Paracetamol can interact with several medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid): - Alcohol: combined use heightens risk of hepatotoxicity. - Warfarin: may enhance anticoagulant effect, increasing bleeding risk. - Rifampicin: can reduce paracetamol plasma levels, diminishing efficacy.

Moderate Interactions (Monitor Closely): - Oral contraceptives: may increase plasma concentrations of paracetamol. - Isoniazid: potential for additive liver stress. - Phenytoin: may alter metabolism, requiring monitoring of liver enzymes.

Frequently asked questions

What is Paracetamol used for?+
Paracetamol is an over‑the‑counter analgesic and antipyretic used to relieve mild to moderate pain such as headache, dental pain, or musculoskeletal discomfort, and to lower fever associated with infections or inflammatory conditions.
How does Paracetamol work?+
Paracetamol works by inhibiting cyclooxygenase enzymes in the central nervous system, which reduces the synthesis of prostaglandins. This action lowers the pain‑signalling threshold and resets the hypothalamic set‑point for temperature regulation, providing analgesic and antipyretic effects.
What is the usual dose of Paracetamol?+
The appropriate dose of Paracetamol is determined by a qualified prescriber based on the patient’s age, weight, clinical condition, and other medications. Patients should follow the specific dosing instructions provided by their healthcare professional.
Is Paracetamol safe during pregnancy or breastfeeding?+
Paracetamol is generally considered compatible with pregnancy and breastfeeding when used at the recommended dose, but the prescriber should evaluate individual risk factors. Women who are pregnant or nursing should discuss use with their healthcare provider.
How do I order Paracetamol from GNH USA?+
To request Paracetamol, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.
How does Paracetamol compare with other analgesics?+
Compared with non‑steroidal anti‑inflammatory drugs (NSAIDs), Paracetamol provides effective pain relief and fever reduction without significant anti‑inflammatory activity or gastrointestinal irritation. However, it lacks the anti‑platelet effects of aspirin and does not address inflammation directly.
How should Paracetamol be stored and handled?+
Paracetamol should be stored at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the product out of reach of children and do not use after the expiry date.
How is Paracetamol administered?+
Paracetamol is administered orally, typically as a tablet, capsule, or liquid formulation. The patient swallows the dose with water, unless a liquid form is prescribed, in which case it is measured with a calibrated device and taken by mouth.
What are the most serious risks associated with Paracetamol?+
The most serious risk is hepatotoxicity, which can occur with overdose or chronic high‑dose use, potentially leading to liver failure. Rare but severe skin reactions such as Stevens‑Johnson syndrome, as well as blood disorders, also represent serious concerns.
Who should not use Paracetamol?+
Paracetamol should be avoided in individuals with known severe liver disease, hypersensitivity to the drug, or those who are taking other medications that could cause dangerous interactions, such as high‑dose alcohol or certain anticoagulants, without medical supervision.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Paracetamol
Route
Oral Use
Manufacturer
Medicinae Sp.Zo.O.
Origin
EU

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