GNH USA

Europe — EMA

Paracetamol

GNH USA supplies Paracetamol (Paracetamol), an Analgesic, Antipyretic for mild to moderate pain and fever. Request a quote for global supply to buyers.

Paracetamol

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What is Paracetamol?

Paracetamol, the active ingredient in Paracetamol, is an Analgesic, Antipyretic presented as a tablet for oral use. It treats mild to moderate pain and fever in adults and children.

GNH USA supplies Paracetamol as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Paracetamol used for?

Paracetamol acts on the prostaglandin pathway to relieve pain and reduce fever.

Headache: provides relief from mild to moderate headache pain. Musculoskeletal pain: reduces discomfort associated with strains, sprains, and backache. Fever: lowers elevated body temperature in febrile states.

What are the side effects of Paracetamol?

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea - Skin rash - Headache

Serious or Rare Side Effects: - Severe liver injury (hepatotoxicity) - Blood disorders such as thrombocytopenia - Allergic reactions including anaphylaxis

What precautions apply to Paracetamol?

Paracetamol should be used with attention to specific safety considerations.

Dose adjustment in liver disease: reduce dose or avoid if severe hepatic impairment. Avoid exceeding recommended daily amount: do not surpass 4 g per day for adults. Use with caution in alcohol consumers: increased risk of liver toxicity. Monitor in renal impairment: dose may need adjustment in severe kidney disease. Pregnancy and breastfeeding: consult a healthcare professional before use. Store at ambient temperature: keep in the original pack, protect from moisture.

What does Paracetamol interact with?

Paracetamol can interact with several medicines; awareness of major and moderate interactions helps ensure safe use.

Major Interactions (Avoid): - Alcohol: heightened risk of hepatotoxicity. - Warfarin: may enhance anticoagulant effect, increasing bleeding risk. - Carbamazepine: can reduce paracetamol's analgesic efficacy.

Moderate Interactions (Monitor Closely): - Isoniazid: potential additive liver stress. - Phenobarbital: may increase paracetamol metabolism, lowering effectiveness. - Phenytoin: may accelerate metabolism, requiring monitoring of pain control.

Frequently asked questions

What is Paracetamol used for?+
Paracetamol is used to relieve mild to moderate pain such as headache, toothache, muscle aches, and to reduce fever associated with common infections. It is an over‑the‑counter option for adults and children when a non‑opioid analgesic is appropriate.
How does Paracetamol work?+
Paracetamol works by inhibiting cyclooxygenase enzymes in the brain and spinal cord, which decreases the production of prostaglandins that sensitize nerve endings to pain and raise the body’s temperature set‑point. This central action provides analgesic and antipyretic effects.
What is the usual dose of Paracetamol?+
The specific dose of Paracetamol is determined by a prescriber or according to the product label. In general, adults may be advised to take up to 1 g per dose, not exceeding 4 g per day, while pediatric dosing is weight‑based. Always follow the healthcare professional’s instructions.
Is Paracetamol safe during pregnancy or breastfeeding?+
Paracetamol’s pregnancy category is listed as unknown, and safety data are limited. Healthcare providers usually consider it when benefits outweigh potential risks, but it should only be used under medical guidance during pregnancy or while breastfeeding.
How do I order Paracetamol from GNH USA?+
To order Paracetamol, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.
How does Paracetamol compare with ibuprofen?+
Paracetamol provides analgesic and antipyretic effects without significant anti‑inflammatory activity, whereas ibuprofen is a non‑steroidal anti‑inflammatory drug (NSAID) that also reduces inflammation. Ibuprofen may cause gastrointestinal irritation and affect platelet function, while Paracetamol carries a higher risk of liver toxicity at excessive doses.
How should Paracetamol be stored and handled?+
Paracetamol tablets should be stored at ambient temperature, below 25 °C, in their original packaging to protect from moisture and light. Keep the container tightly closed and out of reach of children.
How is Paracetamol administered?+
Paracetamol is administered orally, typically as a tablet, capsule, or liquid suspension. It should be swallowed with water, and the dosage form should be taken as directed by a healthcare professional or according to the product label.
What are the most serious risks to watch for when using Paracetamol?+
The most serious risks include severe liver injury, especially when the maximum daily dose is exceeded or combined with alcohol, and rare allergic reactions such as anaphylaxis or severe skin disorders like Stevens‑Johnson syndrome. Prompt medical attention is required if symptoms of liver damage or a severe rash develop.
Who should not use Paracetamol?+
Paracetamol should be avoided by individuals with known hypersensitivity to the drug, those with severe hepatic impairment, and patients who have exceeded the recommended daily dose. Caution is also advised for people with chronic alcohol use or existing liver disease.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Paracetamol
Route
Oral Use
Manufacturer
Sopharma Ad
Origin
EU

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