Pantelmin (Mebendazole)

Mebendazole, the active ingredient in Pantelmin, is an anthelmintic presented as a broad-spectrum anti-parasitic for oral use. It treats a variety of intestinal worm infections in both children and adults.

GNH USA supplies Pantelmin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Mebendazole is employed against helminthic infections that affect the gastrointestinal tract. - Ascariasis: eliminates Ascaris lumbricoides worms and reduces associated abdominal symptoms. - Hookworm infection: eradicates Ancylostoma duodenale and Necator americanus, decreasing intestinal blood loss. - Trichuriasis: removes Trichuris trichiura parasites, relieving diarrhea and rectal irritation.

Adverse reactions to mebendazole are generally mild and reversible.

Common Side Effects: - Abdominal pain - Nausea - Diarrhea - Headache - Dizziness - Rash

Serious or Rare Side Effects: - Hepatotoxicity - Agranulocytosis - Severe skin reactions such as Stevens‑Johnson syndrome - Blood dyscrasias - Anaphylactic reactions

When using Pantelmin, consider the following safety measures: - Pregnancy: avoid use during the first trimester unless clearly needed. - Breastfeeding: consult a healthcare professional before use. - Liver function: monitor if pre‑existing hepatic impairment exists. - Drug interactions: review concomitant medications for potential interactions. - Pediatric use: dosage must be determined by a qualified prescriber. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Mebendazole may affect the plasma concentration of several co‑administered drugs.

Major Interactions (Avoid): - Cytochrome P450 3A4 inducers (e.g., rifampicin, carbamazepine). - Antifungal azoles (e.g., ketoconazole, itraconazole).

Moderate Interactions (Monitor Closely): - Cimetidine - Oral contraceptives - Warfarin - Antiretroviral agents - Antiepileptic drugs