GNH USA

Europe — EMA

Pantadolor (Paracetamol)

GNH USA supplies Pantadolor (Paracetamol), an analgesic for pain and fever, available in rectal formulation for OTC use. Request a quote for global supply.

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What is Paracetamol?

Paracetamol, the active ingredient in Pantadolor, is an analgesic presented as a rectal formulation for OTC use. It treats mild to moderate pain and reduces fever in adults and children when appropriate. GNH USA supplies Pantadolor as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Paracetamol used for?

Pantadolor (paracetamol) acts on the central pain and temperature pathways to relieve discomfort and lower elevated body temperature.

Pain: provides relief of mild to moderate pain such as headache, muscular or dental pain. Fever: reduces fever associated with infections or inflammatory conditions. Headache: alleviates tension‑type headache and other common headache disorders.

What are the side effects of Paracetamol?

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea: mild stomach upset may be experienced. - Abdominal discomfort: occasional stomach pain or discomfort. - Rash: skin redness or mild itching. - Dizziness: transient light‑headedness. - Elevated liver enzymes: mild, usually reversible changes. - Headache: occasional new or worsening headache.

Serious or Rare Side Effects: - Stevens‑Johnson syndrome: severe skin reaction requiring immediate medical attention. - Hepatic failure: rare but potentially life‑threatening liver injury. - Anaphylaxis: acute allergic reaction with breathing difficulty. - Blood dyscrasias: rare cases of agranulocytosis or thrombocytopenia. - Severe skin reactions: toxic epidermal necrolysis. - Renal impairment: rare kidney function decline.

What precautions apply to Paracetamol?

When using Pantodolor, consider the following safety measures.

Assess liver function: avoid use in patients with severe hepatic impairment. Avoid exceeding recommended total daily dose: adhere to maximum limits to prevent toxicity. Use with caution in alcohol users: concurrent alcohol may increase liver risk. Consult healthcare professional before use in children: dosing must be age‑appropriate. Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

What does Paracetamol interact with?

Paracetamol may interact with several medicines; monitoring is advised.

Major Interactions (Avoid): - Warfarin: increased anticoagulant effect may raise bleeding risk. - Carbamazepine: may reduce paracetamol efficacy by enhancing metabolism. - Isoniazid: combined use can heighten risk of liver toxicity.

Moderate Interactions (Monitor Closely): - Oral contraceptives: may reduce contraceptive effectiveness. - Phenytoin: may alter paracetamol clearance. - Alcohol: concurrent use can exacerbate hepatotoxic potential.

Frequently asked questions

What is Pantadolor used for?+
Pantadolor contains paracetamol and is used to relieve mild to moderate pain such as headache, muscular or dental discomfort, and to reduce fever associated with infections or inflammatory conditions. It is an over‑the‑counter option suitable for adults and, when appropriately dosed, for children.
How does paracetamol work?+
Paracetamol works by inhibiting the synthesis of prostaglandins in the central nervous system, especially in the hypothalamus, which controls body temperature. This reduces the perception of pain and lowers the set‑point for fever, providing analgesic and antipyretic effects without significant peripheral anti‑inflammatory activity.
What is the usual dose of Pantadolor?+
The appropriate dose of Pantadolor is determined by a qualified prescriber based on the patient’s age, weight, clinical condition, and overall health status. Healthcare professionals will calculate the exact amount and frequency to ensure safe and effective therapy.
Is Pantadolor safe during pregnancy or breastfeeding?+
Safety data for paracetamol in pregnancy and lactation are limited for this rectal formulation. Women who are pregnant, planning pregnancy, or breastfeeding should consult their healthcare provider before using Pantadolor to weigh potential benefits against any possible risks.
How do I order Pantadolor from GNH USA?+
To order Pantadolor, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.
How does Pantadolor compare with ibuprofen?+
Both Pantadolor (paracetamol) and ibuprofen relieve pain and fever, but they act via different mechanisms. Paracetamol primarily works centrally with minimal anti‑inflammatory effect, while ibuprofen is a non‑steroidal anti‑inflammatory drug that also reduces inflammation. Choice depends on the clinical need, patient tolerance and any contraindications such as gastric or renal concerns.
How should Pantadolor be stored and handled?+
Pantadolor should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability throughout its shelf life.
How is Pantadolor administered?+
Pantadolor is administered rectally. The appropriate suppository is inserted into the rectum, preferably after a bowel movement, and held in place for a few minutes to allow complete dissolution and absorption of the active ingredient.
What are the most serious risks associated with Pantadolor?+
The most serious risks include severe liver injury, especially when exceeding recommended doses or combining with alcohol, and rare allergic reactions such as Stevens‑Johnson syndrome or anaphylaxis. Patients should seek immediate medical attention if they notice signs of liver dysfunction, rash, or breathing difficulties.
Who should not use Pantadolor?+
Pantadolor should be avoided by individuals with known hypersensitivity to paracetamol, those with severe liver disease, and patients who have experienced serious skin reactions to similar drugs. Children under the age specified for the rectal formulation should also not use this product without medical guidance.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Paracetamol
Route
Rectal Use
Manufacturer
Labialfarma - Laboratório De Produtos Farmacêuticos E Nutracêuticos, S.A.
Origin
EU

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