Europe — EMA
Pantadolor (Paracetamol)
GNH USA supplies Pantadolor (Paracetamol), an analgesic for pain and fever, available in rectal formulation for OTC use. Request a quote for global supply.
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What is Paracetamol?
Paracetamol, the active ingredient in Pantadolor, is an analgesic presented as a rectal formulation for OTC use. It treats mild to moderate pain and reduces fever in adults and children when appropriate. GNH USA supplies Pantadolor as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol used for?
Pantadolor (paracetamol) acts on the central pain and temperature pathways to relieve discomfort and lower elevated body temperature.
Pain: provides relief of mild to moderate pain such as headache, muscular or dental pain. Fever: reduces fever associated with infections or inflammatory conditions. Headache: alleviates tension‑type headache and other common headache disorders.
What are the side effects of Paracetamol?
Paracetamol is generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: mild stomach upset may be experienced. - Abdominal discomfort: occasional stomach pain or discomfort. - Rash: skin redness or mild itching. - Dizziness: transient light‑headedness. - Elevated liver enzymes: mild, usually reversible changes. - Headache: occasional new or worsening headache.
Serious or Rare Side Effects: - Stevens‑Johnson syndrome: severe skin reaction requiring immediate medical attention. - Hepatic failure: rare but potentially life‑threatening liver injury. - Anaphylaxis: acute allergic reaction with breathing difficulty. - Blood dyscrasias: rare cases of agranulocytosis or thrombocytopenia. - Severe skin reactions: toxic epidermal necrolysis. - Renal impairment: rare kidney function decline.
What precautions apply to Paracetamol?
When using Pantodolor, consider the following safety measures.
Assess liver function: avoid use in patients with severe hepatic impairment. Avoid exceeding recommended total daily dose: adhere to maximum limits to prevent toxicity. Use with caution in alcohol users: concurrent alcohol may increase liver risk. Consult healthcare professional before use in children: dosing must be age‑appropriate. Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.
What does Paracetamol interact with?
Paracetamol may interact with several medicines; monitoring is advised.
Major Interactions (Avoid): - Warfarin: increased anticoagulant effect may raise bleeding risk. - Carbamazepine: may reduce paracetamol efficacy by enhancing metabolism. - Isoniazid: combined use can heighten risk of liver toxicity.
Moderate Interactions (Monitor Closely): - Oral contraceptives: may reduce contraceptive effectiveness. - Phenytoin: may alter paracetamol clearance. - Alcohol: concurrent use can exacerbate hepatotoxic potential.



